PTSDgene database

Study Report

Study Information
Basic Info
Reference
Citation Nievergelt, C. M., et al. (2015). "Genomic predictors of combat stress vulnerability and resilience in U.S. Marines: A genome-wide association study across multiple ancestries implicates PRTFDC1 as a potential PTSD gene." Psychoneuroendocrinology 51: 459-471.
Phenotype PTSD
Trauma Combat
Study Design Case-control
Study Type Genome-wide association study, Gene-environment interaction study
Sample Size 940 PTSD and 2554 controls
SNP/Marker Size 888,113 SNPs
Predominant Ethnicity Caucasian, Black
Population European, African, Hispanic/Native American, and other descent
Gender All male
Age Cases: mean age=23.0 years, SD=3.0, range from 18 to 38. Control: mean age=23.2 years, SD=3.5, range from 18 to 48.

Detail Info

Genetic result reported by this study
Normal genetic result reported by this study (count: 53)
Marker Phenotype Related Gene Statistical Values Author Comments Marker's Category
rs6482463 PTSD PRTFDC1 Additive model: in EA (European American) sample: OR=1.41, SE=0.08, P-value=2.98E-05; in AA (African American) sample: OR=1.49, SE=0.26, P-value=0.118; in HNA (Hispanic and Native American descent) sample: OR=1.58, SE=0.14, P-value=1.25E-03; in OTH (other) sample: OR=1.55, SE=0.18, P-value=0.012; meta-analysis in four Marine Resiliency Study(MRS) groups: OR=1.47, SE=0.06, P-value=2.04E-09, P-value=0.90 for Cochran's Q. Recessive genetic models: P-value=2.03E-03, dominant genetic models: P-value=3.2E-09. Cumulative model including SNP, age, LEC, CTQ and prior deployment (plus the standard covariates battalion, GWAS platform, and 5 PC's for ancestry) in predicting PTSD status P-value=4.07E-94 and explained about 20% of the variance. We found evidence for PRTFDC1 as a potential novel PTSD gene...... We found evidence for PRTFDC1 as a potential novel PTSD gene. More... Significant
rs6528940 PTSD MAGEC1 In subjects of European: P-value=1.3E-06. It met the threshold for suggestive evidence of association ...... It met the threshold for suggestive evidence of association (P-value<5E-06). More... Trend
rs6314 PTSD HTR2A In 2179 MRS subjects of European descent: P-value=0.049. P-value is nominally significant (P-value<0.05). P-value is nominally significant (P-value<0.05). Significant
rs6759539 PTSD LINC01090 In 2179 MRS subjects of European descent: P-value=0.002. P-value is nominally significant (P-value<0.05). P-value is nominally significant (P-value<0.05). Significant
rs6681010 PTSD FASLG In meta-analysis: P-value=2.0E-06. It met the threshold for suggestive evidence of association ...... It met the threshold for suggestive evidence of association (P-value<5E-06). More... Trend
rs73220799 PTSD PLXNC1 In subjects of European: P-value=4.3E-06. In meta-analysis: P-value=4.4E-07. It met the threshold for suggestive evidence of association ...... It met the threshold for suggestive evidence of association (P-value<5E-06). More... Trend
rs6968349 PTSD ADCYAP1R1 In 2179 MRS subjects of European descent: P-value=0.017. P-value is nominally significant (P-value<0.05). P-value is nominally significant (P-value<0.05). Significant
rs77929608 PTSD SRD5A2 In 2179 MRS subjects of European descent: P-value=0.049. P-value is nominally significant (P-value<0.05). P-value is nominally significant (P-value<0.05). Significant
rs75924850 PTSD DRD2 In 2179 MRS subjects of European descent: P-value=0.021. P-value is nominally significant (P-value<0.05). P-value is nominally significant (P-value<0.05). Significant
rs74939664 PTSD ADGRL2 In subjects of European: P-value=2.0E-06. It met the threshold for suggestive evidence of association ...... It met the threshold for suggestive evidence of association (P-value<5E-06). More... Trend
rs1033962 PTSD PRTFDC1 Additive model: in EA (European American) sample: OR=1.40, SE=0.08, P-value=4.48E-05; in AA (African American) sample: OR=1.45, SE=0.25, P-value=0.148; in HNA (Hispanic and Native American descent) sample: OR=1.57, SE=0.14, P-value=1.37E-03; in OTH (other) sample: OR=1.52, SE=0.17, P-value=0.016; meta-analysis in four Marine Resiliency Study(MRS) groups: OR=1.45, SE=0.06, P-value=4.93E-09, P-value=0.90 for Cochran's Q; in an independent replication sample from the National Center for PTSD/Boston (NCPTS): OR=1.28, SE=0.17, P-value=0.144, P-value=0.90 for Cochran's Q; meta-analysis in MRS groups and NCPTS: OR=1.43, SE=0.06, P-value=2.06E-09, P-value=0.91 for Cochran's Q. We found evidence for PRTFDC1 as a potential novel PTSD gene...... We found evidence for PRTFDC1 as a potential novel PTSD gene. More... Significant
rs10457838 PTSD UST In subjects of African: P-value=2.2E-06. It met the threshold for suggestive evidence of association ...... It met the threshold for suggestive evidence of association (P-value<5E-06). More... Trend
rs363238 PTSD SLC18A2 In 2179 MRS subjects of European descent: P-value=0.022. P-value is nominally significant (P-value<0.05). P-value is nominally significant (P-value<0.05). Significant
rs28914827 PTSD SLC6A4 In 2179 MRS subjects of European descent: P-value=0.14. No significant result. No significant result. Non-significant
rs3100127 PTSD LGR6 In subjects of African: P-value=1.3E-06. It met the threshold for suggestive evidence of association ...... It met the threshold for suggestive evidence of association (P-value<5E-06). More... Trend
rs10511822 PTSD LINGO2 In subjects of European: P-value=3.1E-06. It met the threshold for suggestive evidence of association ...... It met the threshold for suggestive evidence of association (P-value<5E-06). More... Trend
rs4511180 PTSD PTPRVP In subjects of African: P-value=7.7E-07. It met the threshold for suggestive evidence of association ...... It met the threshold for suggestive evidence of association (P-value<5E-06). More... Trend
rs4916008 PTSD JAK1 In subjects of European: P-value=4.0E-06. It met the threshold for suggestive evidence of association ...... It met the threshold for suggestive evidence of association (P-value<5E-06). More... Trend
rs4838092 PTSD LHX2 In subjects of African: P-value=9.0E-07. It met the threshold for suggestive evidence of association ...... It met the threshold for suggestive evidence of association (P-value<5E-06). More... Trend
rs4659395 PTSD STMN1 In 2179 MRS subjects of European descent: P-value=0.09. No significant result. No significant result. Non-significant
rs62275374 PTSD LRPAP1 In subjects of European: P-value=4.5E-06. It met the threshold for suggestive evidence of association ...... It met the threshold for suggestive evidence of association (P-value<5E-06). More... Trend
rs518425 PTSD CHRNA5 In 2179 MRS subjects of European descent: P-value=0.07. No significant result. No significant result. Non-significant
rs4987059 PTSD DRD4 In 2179 MRS subjects of European descent: P-value=0.10. No significant result. No significant result. Non-significant
rs544437 PTSD TPH1 In 2179 MRS subjects of European descent: P-value=0.25. No significant result. No significant result. Non-significant
rs139604943 PTSD ANK3 In 2179 MRS subjects of European descent: P-value=0.008. P-value is nominally significant (P-value<0.05). P-value is nominally significant (P-value<0.05). Significant
rs141129523 PTSD RGS2 In 2179 MRS subjects of European descent: P-value=0.022. P-value is nominally significant (P-value<0.05). P-value is nominally significant (P-value<0.05). Significant
rs1380630 PTSD LOC729307 In meta-analysis: P-value=1.9E-06. It met the threshold for suggestive evidence of association ...... It met the threshold for suggestive evidence of association (P-value<5E-06). More... Trend
rs138384996 PTSD UBE2U In meta-analysis: P-value=4.1E-07. It met the threshold for suggestive evidence of association ...... It met the threshold for suggestive evidence of association (P-value<5E-06). More... Trend
rs12442490 PTSD RORA In 2179 MRS subjects of European descent: P-value=0.003. P-value is nominally significant (P-value<0.05). P-value is nominally significant (P-value<0.05). Significant
rs116897693 PTSD CRHR1 In 2179 MRS subjects of European descent: P-value=0.023. P-value is nominally significant (P-value<0.05). P-value is nominally significant (P-value<0.05). Significant
rs116647843 PTSD DTNBP1 In 2179 MRS subjects of European descent: P-value=0.06. No significant result. No significant result. Non-significant
rs115028822 PTSD SERAC1 In meta-analysis: P-value=1.6E-06. It met the threshold for suggestive evidence of association ...... It met the threshold for suggestive evidence of association (P-value<5E-06). More... Trend
rs113712660 PTSD TLL1 In 2179 MRS subjects of European descent: P-value=0.017. P-value is nominally significant (P-value<0.05). P-value is nominally significant (P-value<0.05). Significant
rs1081105 PTSD APOE In 2179 MRS subjects of European descent: P-value=0.05. P-value is suggestive significant (P-value=0.05). P-value is suggestive significant (P-value=0.05). Non-significant
rs10737854 PTSD RGS7 In subjects of European: P-value=4.6E-06. It met the threshold for suggestive evidence of association ...... It met the threshold for suggestive evidence of association (P-value<5E-06). More... Trend
rs78826942 PTSD FRMD5 In meta-analysis: P-value=3.8E-06. It met the threshold for suggestive evidence of association ...... It met the threshold for suggestive evidence of association (P-value<5E-06). More... Trend
rs2616978 PTSD CSMD1 In subjects of Hispanic/Native American (HNA): P-value=2.8E-06. It met the threshold for suggestive evidence of association ...... It met the threshold for suggestive evidence of association (P-value<5E-06). More... Trend
rs79485117 PTSD KDM7A In meta-analysis: P-value=4.4E-07. It met the threshold for suggestive evidence of association ...... It met the threshold for suggestive evidence of association (P-value<5E-06). More... Trend
rs79590198 PTSD NR3C1 In 2179 MRS subjects of European descent: P-value=0.09. No significant result. No significant result. Non-significant
rs2471320 PTSD JHDM1D-AS1 In meta-analysis: P-value=4.2E-06. It met the threshold for suggestive evidence of association ...... It met the threshold for suggestive evidence of association (P-value<5E-06). More... Trend
rs2312236 PTSD POGK In subjects of Hispanic/Native American (HNA): P-value=2.9E-06. It met the threshold for suggestive evidence of association ...... It met the threshold for suggestive evidence of association (P-value<5E-06). More... Trend
rs9366890 PTSD FKBP5 In 2179 MRS subjects of European descent: P-value=0.015. P-value is nominally significant (P-value<0.05). P-value is nominally significant (P-value<0.05). Significant
rs187093517 PTSD UBE2E3 In subjects of European: P-value= 2.8E-07. It met the threshold for suggestive evidence of association ...... It met the threshold for suggestive evidence of association (P-value<5E-06). More... Trend
rs199563271 PTSD PTPRT In subjects of European: P-value=1.4E-06. It met the threshold for suggestive evidence of association ...... It met the threshold for suggestive evidence of association (P-value<5E-06). More... Trend
rs2148269 PTSD PRTFDC1 In subjects of European: P-value=4.6E-06. In meta-analysis: P-value=8.0E-07. It met the threshold for suggestive evidence of association ...... It met the threshold for suggestive evidence of association (P-value<5E-06). More... Trend
rs9545302 PTSD LINC01080 In subjects of European: P-value=1.4E-06. It met the threshold for suggestive evidence of association ...... It met the threshold for suggestive evidence of association (P-value<5E-06). More... Trend
rs183063707 PTSD TPH2 In 2179 MRS subjects of European descent: P-value=0.017. P-value is nominally significant (P-value<0.05). P-value is nominally significant (P-value<0.05). Significant
rs17551315 PTSD WWC1 In 2179 MRS subjects of European descent: P-value=0.001. P-value is nominally significant (P-value<0.05). P-value is nominally significant (P-value<0.05). Significant
rs174686 PTSD COMT In 2179 MRS subjects of European descent: P-value=0.049. P-value is nominally significant (P-value<0.05). P-value is nominally significant (P-value<0.05). Significant
rs148952004 PTSD PPM1N In subjects of European: P-value=3.8E-06. In meta-analysis: P-value=1.8E-06. It met the threshold for suggestive evidence of association ...... It met the threshold for suggestive evidence of association (P-value<5E-06). More... Trend
rs148139959 PTSD GABRA2 In 2179 MRS subjects of European descent: P-value=0.024. P-value is nominally significant (P-value<0.05). P-value is nominally significant (P-value<0.05). Significant
rs144782362 PTSD SLC6A3 In 2179 MRS subjects of European descent: P-value=0.008. P-value is nominally significant (P-value<0.05). P-value is nominally significant (P-value<0.05). Significant
rs142570922 PTSD CYP11B1 In meta-analysis: P-value=3.8E-06. It met the threshold for suggestive evidence of association ...... It met the threshold for suggestive evidence of association (P-value<5E-06). More... Trend

Gene * Environment result reported by this study (count: 52)
Marker Phenotype Related Gene Environment Statistical Values Author Comments Marker's Category
rs10511822 PTSD LINGO2 Childhood trauma Gene and childhood trauma interaction: P-value<0.05 in any subjects. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs10737854 PTSD RGS7 Childhood trauma Gene and childhood trauma interaction: P-value<0.05 in any subjects. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs1081105 PTSD APOE Childhood trauma In 2179 MRS subjects of European descent, gene and childhood trauma interaction: P-value=0.036. It showed a significant interaction effect with childhood tr...... It showed a significant interaction effect with childhood trauma on PTSD. More... Significant
rs113712660 PTSD TLL1 Childhood trauma In 2179 MRS subjects of European descent, gene and childhood trauma interaction: P-value<0.05. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs115028822 PTSD SERAC1 Childhood trauma Gene and childhood trauma interaction: P-value<0.05 in any subjects. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs116647843 PTSD DTNBP1 Childhood trauma In 2179 MRS subjects of European descent, gene and childhood trauma interaction: P-value<0.05. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs116897693 PTSD CRHR1 Childhood trauma In 2179 MRS subjects of European descent, gene and childhood trauma interaction: P-value<0.05. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs12442490 PTSD RORA Childhood trauma In 2179 MRS subjects of European descent, gene and childhood trauma interaction: P-value<0.05. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs10457838 PTSD UST Childhood trauma Gene and childhood trauma interaction: P-value<0.05 in any subjects. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs174686 PTSD COMT Childhood trauma In 2179 MRS subjects of European descent, gene and childhood trauma interaction: P-value<0.05. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs148952004 PTSD PPM1N Childhood trauma Gene and childhood trauma interaction: P-value<0.05 in any subjects. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs148139959 PTSD GABRA2 Childhood trauma In 2179 MRS subjects of European descent, gene and childhood trauma interaction: P-value<0.05. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs199563271 PTSD PTPRT Childhood trauma In subjects of African, gene and childhood trauma interaction: P-value=0.020. It showed a significant interaction effect with childhood tr...... It showed a significant interaction effect with childhood trauma on PTSD. More... Significant
rs187093517 PTSD UBE2E3 Childhood trauma Gene and childhood trauma interaction: P-value<0.05 in any subjects. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs183063707 PTSD TPH2 Childhood trauma In 2179 MRS subjects of European descent, gene and childhood trauma interaction: P-value<0.05. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs17551315 PTSD WWC1 Childhood trauma In 2179 MRS subjects of European descent, gene and childhood trauma interaction: P-value<0.05. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs138384996 PTSD UBE2U Childhood trauma Gene and childhood trauma interaction: P-value<0.05 in any subjects. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs1380630 PTSD LOC729307 Childhood trauma Gene and childhood trauma interaction: P-value<0.05 in any subjects. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs144782362 PTSD SLC6A3 Childhood trauma In 2179 MRS subjects of European descent, gene and childhood trauma interaction: P-value<0.05. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs142570922 PTSD CYP11B1 Childhood trauma In subjects of Hispanic/Native American, gene and childhood trauma interaction: P-value=0.036. In other descents, gene and childhood trauma interaction: P-value=0.027. It showed a significant interaction effect with childhood tr...... It showed a significant interaction effect with childhood trauma on PTSD. More... Significant
rs141129523 PTSD RGS2 Childhood trauma In 2179 MRS subjects of European descent, gene and childhood trauma interaction: P-value<0.05. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs139604943 PTSD ANK3 Childhood trauma In 2179 MRS subjects of European descent, gene and childhood trauma interaction: P-value<0.05. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs4838092 PTSD LHX2 Childhood trauma Gene and childhood trauma interaction: P-value<0.05 in any subjects. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs4511180 PTSD PTPRVP Childhood trauma Gene and childhood trauma interaction: P-value<0.05 in any subjects. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs4659395 PTSD STMN1 Childhood trauma In 2179 MRS subjects of European descent, gene and childhood trauma interaction: P-value<0.05. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs518425 PTSD CHRNA5 Childhood trauma In 2179 MRS subjects of European descent, gene and childhood trauma interaction: P-value<0.05. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs544437 PTSD TPH1 Childhood trauma In 2179 MRS subjects of European descent, gene and childhood trauma interaction: P-value<0.05. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs4916008 PTSD JAK1 Childhood trauma Gene and childhood trauma interaction: P-value<0.05 in any subjects. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs4987059 PTSD DRD4 Childhood trauma In 2179 MRS subjects of European descent, gene and childhood trauma interaction: P-value<0.05. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs2471320 PTSD JHDM1D-AS1 Childhood trauma In subjects of African, gene and childhood trauma interaction: P-value=0.003. It showed a significant interaction effect with childhood tr...... It showed a significant interaction effect with childhood trauma on PTSD. More... Significant
rs2148269 PTSD PRTFDC1 Childhood trauma Gene and childhood trauma interaction: P-value<0.05 in any subjects. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs2312236 PTSD POGK Childhood trauma Gene and childhood trauma interaction: P-value<0.05 in any subjects. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs3100127 PTSD LGR6 Childhood trauma Gene and childhood trauma interaction: P-value<0.05 in any subjects. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs363238 PTSD SLC18A2 Childhood trauma In 2179 MRS subjects of European descent, gene and childhood trauma interaction: P-value<0.05. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs2616978 PTSD CSMD1 Childhood trauma In subjects of African, gene and childhood trauma interaction: P-value=0.050. It showed a suggestive interaction effect with childhood tra...... It showed a suggestive interaction effect with childhood trauma on PTSD. More... Non-significant
rs28914827 PTSD SLC6A4 Childhood trauma In 2179 MRS subjects of European descent, gene and childhood trauma interaction: P-value<0.05. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs74939664 PTSD ADGRL2 Childhood trauma Gene and childhood trauma interaction: P-value<0.05 in any subjects. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs75924850 PTSD DRD2 Childhood trauma In 2179 MRS subjects of European descent, gene and childhood trauma interaction: P-value<0.05. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs6968349 PTSD ADCYAP1R1 Childhood trauma In 2179 MRS subjects of European descent, gene and childhood trauma interaction: P-value<0.05. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs6759539 PTSD LINC01090 Childhood trauma In 2179 MRS subjects of European descent, gene and childhood trauma interaction: P-value<0.05. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs73220799 PTSD PLXNC1 Childhood trauma Gene and childhood trauma interaction: P-value<0.05 in any subjects. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs6482463 PTSD PRTFDC1 Childhood trauma Gene and childhood trauma interaction: P-value<0.05 in any subjects. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs6314 PTSD HTR2A Childhood trauma In 2179 MRS subjects of European descent, gene and childhood trauma interaction: P-value<0.05. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs6681010 PTSD FASLG Childhood trauma Gene and childhood trauma interaction: P-value<0.05 in any subjects. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs6528940 PTSD MAGEC1 Childhood trauma Gene and childhood trauma interaction: P-value<0.05 in any subjects. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs62275374 PTSD LRPAP1 Childhood trauma In subjects of European, gene and childhood trauma interaction: P-value=0.006. It showed a significant interaction effect with childhood tr...... It showed a significant interaction effect with childhood trauma on PTSD. More... Significant
rs9545302 PTSD LINC01080 Childhood trauma Gene and childhood trauma interaction: P-value<0.05 in any subjects. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs9366890 PTSD FKBP5 Childhood trauma In 2179 MRS subjects of European descent, gene and childhood trauma interaction: P-value<0.05. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs77929608 PTSD SRD5A2 Childhood trauma In 2179 MRS subjects of European descent, gene and childhood trauma interaction: P-value<0.05. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs78826942 PTSD FRMD5 Childhood trauma Gene and childhood trauma interaction: P-value<0.05 in any subjects. It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant
rs79485117 PTSD KDM7A Childhood trauma In subjects of African, gene and childhood trauma interaction: P-value=0.027. It showed a significant interaction effect with childhood tr...... It showed a significant interaction effect with childhood trauma on PTSD. More... Significant
rs79590198 PTSD NR3C1 Childhood trauma In 2179 MRS subjects of European descent, gene and childhood trauma interaction: P-value=0.022. It showed a significant interaction effect with childhood tr...... It showed a significant interaction effect with childhood trauma on PTSD. More... Significant