PTSDgene database

Gene Report

Basic Info
Approved Symbol DRD2
Approved Name dopamine receptor D2
Location 11q23.2
Position chr11:113409615-113475691, -1
External Links HGNC: 3023
Entrez Gene: 1813
Ensembl: ENSG00000149295
UCSC: uc001poa.4
No. of Association Results 18 (Positive: 11; Negative: 7; trend: 0)
Annotation Type Literature-origin, Mapped by Literature SNP, Mapped by LD-proxy
Gene related association results
Normal genetic study related association results (count: 18)
Reference Phenotype Marker Gene's Category
Tian, Y.,2015 PTSD DRD2_Taq 1 Significant
Young, R. M.,2002 PTSD DRD2_Taq I A alleles Significant
Duan, Z.,2015 PTSD diagnosis rs10891556 - rs1799978 - rs4648317 - rs7131056 - rs4460839 - rs12574471 - rs4648319 - rs4648318 - rs4586205 - rs4436578 - rs2075652 - rs2734833 - rs6279 - rs2242591 - rs1800479, GTGATCATTTGGCTA ; rs10891556 - rs1799978 - rs4648317 - rs7131056 - rs4460839 - rs12574471 - rs4648319 - rs4648318 - rs4586205 - rs4436578 - rs2075652 - rs2734833 - rs6279 - rs2242591 - rs1800479, GTGATCGCGCAGGCG ; rs10891556 - rs1799978 - rs4648317 - rs7131056 - rs4460839 - rs12574471 - rs4648319 - rs4648318 - rs4586205 - rs4436578 - rs2075652 - rs2734833 - rs6279 - rs2242591 - rs1800479, TTACTCATTTGGCTA ; rs10891556 - rs1799978 - rs4648317 - rs7131056 - rs4460839 - rs12574471 - rs4648319 - rs4648318 - rs4586205 - rs4436578 - rs2075652 - rs2734833 - rs6279 - rs2242591 - rs1800479, TTACTCGCGCAGGCG ; rs10891556 ; rs12574471 ; rs1799978 ; rs1800479 ; rs2075652 ; rs2242591 ; rs2734833 ; rs4436578 ; rs4460839 ; rs4586205 ; rs4648317 ; rs4648318 ; rs4648319 ; rs6279 ; rs7131056 Significant
Comings, D. E.,1996 Avoidance of trauma-associated stimuli rs1800497 Significant
Comings, D. E.,1996 Increased hyperreactivity and vigilance rs1800497 Significant
Nelson, E. C.,2014 PTSD rs12364283 ; rs12805897 ; rs4648317 Significant
Voisey, J.,2009 PTSD rs1799732 ; rs1800497 ; rs6277 Significant
Nievergelt, C. M.,2015 PTSD rs75924850 Significant
Bailey, J. N.,2010 PTSD category B symptom score rs1800497 Non-significant
Bailey, J. N.,2010 PTSD category C symptom score rs1800497 Non-significant
Solovieff, N.,2014 PTSD diagnosis rs1124492 Non-significant
Comings, D. E.,1996 PTSD diagnosis rs1800497 Significant
Gelernter, J.,1999 PTSD diagnosis rs1800497 Non-significant
Bailey, J. N.,2010 PTSD diagnosis rs1800497 Non-significant
Solovieff, N.,2014 PTSD severity rs4274224 Non-significant
Bailey, J. N.,2010 PTSD symptoms rs1800497 Non-significant
Comings, D. E.,1996 Reexperiencing of the traumatic events rs1800497 Significant
Comings, D. E.,1996 Total PTSD score rs1800497 Significant
G*E study related association result (count: 1)
Reference Phenotype Environment Marker Gene's Category
Nievergelt, C. M.,2015 PTSD Childhood trauma rs75924850 ; DRD2_Taq 1 Non-significant
Gene functional annotation
Gene related GO terms (count: 117)

Gene related KEGG pathways (count: 2)

Gene related interactors from protein-protein interactions data in PINA v2 (count: 19)