PTSDgene database

Gene Report

Basic Info
Approved Symbol NR3C1
Previous Symbol GRL
Symbol Alias GR
Approved Name nuclear receptor subfamily 3 group C member 1
Previous Name "nuclear receptor subfamily 3, group C, member 1|nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)"
Name Alias glucocorticoid receptor
Location 5q31-q32
Position chr5:143277931-143435512, -1
External Links HGNC: 7978
Entrez Gene: 2908
Ensembl: ENSG00000113580
UCSC: uc003lnb.3
No. of Association Results 6 (Positive: 2; Negative: 4; trend: 0)
Annotation Type Literature-origin, Mapped by Literature SNP, Mapped by LD-proxy, rSNP target
Gene related association results
Normal genetic study related association results (count: 6)
Reference Phenotype Marker Gene's Category
Bachmann, A. W.,2005 PTSD diagnosis GR_exon 2_N363S ; GR_exon_R23K ; GR_intron 2_Bcl1 Non-significant
Hauer, D.,2011 PTSD stress symptom scores GR_intron 2_Bcl1 Significant
Lian, Y.,2014 PTSD rs10482605 ; rs258747 ; rs41423247 Significant
Nievergelt, C. M.,2015 PTSD rs79590198 Non-significant
Solovieff, N.,2014 PTSD diagnosis rs7701443 Non-significant
Solovieff, N.,2014 PTSD severity rs7701443 Non-significant
G*E study related association result (count: 1)
Reference Phenotype Environment Marker Gene's Category
Nievergelt, C. M.,2015 PTSD Childhood trauma rs79590198 Significant
Gene functional annotation
Gene related GO terms (count: 35)

Gene related KEGG pathways (count: 1)

Gene related interactors from protein-protein interactions data in PINA v2 (count: 179)