PTSDgene database

SNP Report

Basic Info
Name rs10511822 dbSNP Ensembl
Location 9:28127794 - 28127794(+)
Variant Seq T
Ancestral Allele C
Ref Seq C
Minor Allele Frequence 0.159145
Annotation intron_variant; non_coding_transcript_variant
Variant Effect intron_variant(ENST00000379992, ENST00000308675, ENST00000613945, ENST00000493941); non_coding_transcript_variant(ENST00000493941)
SIFT Annotation deleterious
SIFT Variant Effect deleterious(ENST00000613945, ENST00000308675, ENST00000379992)
PolyPhen Annotation probably_damaging
PolyPhen Variant Effect probably_damaging(ENST00000613945, ENST00000308675, ENST00000379992)
rSNP? No Link in rVarBase
Related Regulatory Elements n/a
Chromatin State Inactive region
No. of Marker's Association Results 1 (Positive: 0; Negative: 0; Trend: 1)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Nievergelt, C. M.,2015 PTSD In subjects of European: P-value=3.1E-06. In subjects of European: P-value=3.1E-06. It met the threshold for suggestive evidence of association ...... It met the threshold for suggestive evidence of association (P-value<5E-06). More... Trend
G*E study related association result (count: 1)
Reference Phenotype Environment Statistical Values Author Comments Marker's Category
Nievergelt, C. M.,2015 PTSD Childhood trauma Gene and childhood trauma interaction: P-value<0.05 in any s...... Gene and childhood trauma interaction: P-value<0.05 in any subjects. More... It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant


SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
LINGO2 leucine rich repeat and Ig domain containing 2 9p21.2 1(0/0/1)

SNPs in LD with rs10511822 (count: 4)
The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 4)


SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
RP11-707O23.5 No Adipose Subcutaneous cis GTEx