
Gene Report
Approved Symbol | HTR2A |
---|---|
Previous Symbol | HTR2 |
Symbol Alias | 5-HT2A |
Approved Name | 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled |
Previous Name | 5-hydroxytryptamine (serotonin) receptor 2A |
Location | 13q14-q21 |
Position | chr13:46831550-46897076, -1 |
External Links |
HGNC: 5293 Entrez Gene: 3356 Ensembl: ENSG00000102468 UCSC: uc010acr.4 |
No. of Association Results | 4 (Positive: 2; Negative: 2; trend: 0) |
Annotation Type | Literature-origin, Mapped by Literature SNP, Mapped by LD-proxy |
Reference | Phenotype | Marker | Gene's Category |
---|---|---|---|
Mellman, T. A.,2009 | PTSD | rs6311 | Significant |
Nievergelt, C. M.,2015 | PTSD | rs6314 | Significant |
Solovieff, N.,2014 | PTSD diagnosis | rs10507545 | Non-significant |
Solovieff, N.,2014 | PTSD severity | rs9534507 | Non-significant |
Reference | Phenotype | Environment | Marker | Gene's Category |
---|---|---|---|---|
Nievergelt, C. M.,2015 | PTSD | Childhood trauma | rs6314 | Non-significant |
ID | Name | No. of Genes in PTSDgene |
---|---|---|
hsa04020 | Calcium signaling pathway | 11 |
hsa04540 | Gap junction | 6 |
hsa04080 | Neuroactive ligand-receptor interaction | 22 |
Gene | Interactor | Interactor in PTSDgene? | Experiment Method | Interaction Type | PMID |
---|---|---|---|---|---|
HTR2A | NME3 | No | -- | -- | 16537434 |
HTR2A | PON2 | No | -- | -- | 16537434 |
HTR2A | MRPL28 | No | -- | -- | 16537434 |
HTR2A | PPP5C | No | -- | -- | 16537434 |
HTR2A | MAP1A | No | -- | -- | 16537434 |
HTR2A | GNAI1 | No | -- | -- | 11916537 |
HTR2A | ANKS1B | No | -- | -- | 16537434 |
HTR2A | GNA11 | No | -- | -- | 11916537 |
HTR2A | RPS6KA3 | No | -- | -- | 16537434 |
HTR2A | DLG4 | No | -- | -- | 12682061 , 12682061 |
HTR2A | GNAQ | No | -- | -- | 11916537 |
HTR2A | NTRK3 | No | -- | -- | 16537434 |
Copyright: Key Lab of Mental Health, Institute of Psychology, Chinese Academy of Sciences Feedback
Last update: April 1, 2018