SNP Report
Basic Info
| Name | rs28914827 dbSNP Ensembl | ||
|---|---|---|---|
| Location | 17:30222791 - 30222791(+) | ||
| Variant Seq | T | ||
| Ancestral Allele | C | ||
| Ref Seq | C | ||
| Minor Allele Frequence | 0.00678914 | ||
| Annotation | intron_variant | ||
| Variant Effect | intron_variant(ENST00000394821, ENST00000261707, ENST00000401766) | ||
| SIFT Annotation | deleterious | ||
| SIFT Variant Effect | deleterious(ENST00000394821, ENST00000261707, ENST00000401766) | ||
| PolyPhen Annotation | probably_damaging | ||
| PolyPhen Variant Effect | probably_damaging(ENST00000394821, ENST00000261707, ENST00000401766) | ||
| rSNP? | Yes Link in rVarBase | ||
| Related Regulatory Elements | Chromatin interactive region | ||
| Chromatin State | Enhancers;Flanking Active TSS;Active TSS;Weak transcription | ||
| No. of Marker's Association Results | 1 (Positive: 0; Negative: 1; Trend: 0) | ||
| Source | Literature | ||
SNP related association results
| Reference | Phenotype | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|
| Nievergelt, C. M.,2015 | PTSD | In 2179 MRS subjects of European descent: P-value=0.14. In 2179 MRS subjects of European descent: P-value=0.14. | No significant result. No significant result. | Non-significant |
G*E study related association result (count: 1)
| Reference | Phenotype | Environment | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|---|
| Nievergelt, C. M.,2015 | PTSD | Childhood trauma | In 2179 MRS subjects of European descent, gene and childhood...... In 2179 MRS subjects of European descent, gene and childhood trauma interaction: P-value<0.05. More... | It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... | Non-significant |
SNP related genes (count: 1)
| Approved Symbol | Approved Name | Location | No. of Association Results (Positive/Negative/Trend)  |
|---|---|---|---|
| SLC6A4 | solute carrier family 6 (neurotransmitter transporter), member 4 | 17q11.2 | 44(13/31/0) |
SNPs in LD with rs28914827 (count: 1)
Literature-origin SNPs (count: 0)
LD-proxies (count: 1)
SNP related eQTL (count: 1)