SNP Report
Basic Info
| Name | rs78826942 dbSNP Ensembl | ||
|---|---|---|---|
| Location | 15:44103716 - 44103716(+) | ||
| Variant Seq | C | ||
| Ancestral Allele | T | ||
| Ref Seq | T | ||
| Minor Allele Frequence | 0.01877 | ||
| Annotation | intron_variant; NMD_transcript_variant | ||
| Variant Effect | intron_variant(ENST00000421674, ENST00000451277, ENST00000484674, ENST00000417257, ENST00000402883, ENST00000458630); NMD_transcript_variant(ENST00000421674, ENST00000451277, ENST00000458630) | ||
| SIFT Annotation | deleterious | ||
| SIFT Variant Effect | deleterious(ENST00000421674, ENST00000449926, ENST00000402883, ENST00000451277, ENST00000458630, ENST00000417257) | ||
| PolyPhen Annotation | probably_damaging | ||
| PolyPhen Variant Effect | probably_damaging(ENST00000421674, ENST00000449926, ENST00000402883, ENST00000451277, ENST00000458630, ENST00000417257) | ||
| rSNP? | Yes Link in rVarBase | ||
| Related Regulatory Elements | n/a | ||
| Chromatin State | Weak transcription;Bivalent Enhancer;Enhancers | ||
| No. of Marker's Association Results | 1 (Positive: 0; Negative: 0; Trend: 1) | ||
| Source | Literature | ||
SNP related association results
| Reference | Phenotype | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|
| Nievergelt, C. M.,2015 | PTSD | In meta-analysis: P-value=3.8E-06. In meta-analysis: P-value=3.8E-06. | It met the threshold for suggestive evidence of association ...... It met the threshold for suggestive evidence of association (P-value<5E-06). More... | Trend |
G*E study related association result (count: 1)
| Reference | Phenotype | Environment | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|---|
| Nievergelt, C. M.,2015 | PTSD | Childhood trauma | Gene and childhood trauma interaction: P-value<0.05 in any s...... Gene and childhood trauma interaction: P-value<0.05 in any subjects. More... | It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... | Non-significant |
SNP related genes (count: 1)
| Approved Symbol | Approved Name | Location | No. of Association Results (Positive/Negative/Trend)  |
|---|---|---|---|
| FRMD5 | FERM domain containing 5 | 15q15.3 | 1(0/0/1) |
SNPs in LD with rs78826942 (count: 0)
SNP related eQTL (count: 1)