PTSDgene database

SNP Report

Basic Info
Name rs6968349 dbSNP Ensembl
Location 7:31072002 - 31072002(+)
Variant Seq C,T
Ref Seq G
Minor Allele Frequence 0.402756
Annotation intron_variant
Variant Effect intron_variant(ENST00000409489, ENST00000396211, ENST00000431811, ENST00000409363, ENST00000614107, ENST00000304166)
SIFT Annotation deleterious; tolerated
SIFT Variant Effect deleterious(ENST00000431811); tolerated(ENST00000304166, ENST00000409489, ENST00000614107, ENST00000409363, ENST00000396211)
PolyPhen Annotation benign; possibly_damaging
PolyPhen Variant Effect benign(ENST00000431811, ENST00000304166); possibly_damaging(ENST00000409489, ENST00000614107, ENST00000409363, ENST00000396211)
rSNP? No Link in rVarBase
Related Regulatory Elements n/a
Chromatin State Inactive region
No. of Marker's Association Results 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Nievergelt, C. M.,2015 PTSD In 2179 MRS subjects of European descent: P-value=0.017. In 2179 MRS subjects of European descent: P-value=0.017. P-value is nominally significant (P-value<0.05). P-value is nominally significant (P-value<0.05). Significant
G*E study related association result (count: 1)
Reference Phenotype Environment Statistical Values Author Comments Marker's Category
Nievergelt, C. M.,2015 PTSD Childhood trauma In 2179 MRS subjects of European descent, gene and childhood...... In 2179 MRS subjects of European descent, gene and childhood trauma interaction: P-value<0.05. More... It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant


SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 7p14.3 19(8/11/0)

SNPs in LD with rs6968349 (count: 0)

SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
LRRC37A4P No Adipose Subcutaneous cis GTEx