SNP Report
Basic Info
| Name | rs6968349 dbSNP Ensembl | ||
|---|---|---|---|
| Location | 7:31072002 - 31072002(+) | ||
| Variant Seq | C,T | ||
| Ref Seq | G | ||
| Minor Allele Frequence | 0.402756 | ||
| Annotation | intron_variant | ||
| Variant Effect | intron_variant(ENST00000409489, ENST00000396211, ENST00000431811, ENST00000409363, ENST00000614107, ENST00000304166) | ||
| SIFT Annotation | deleterious; tolerated | ||
| SIFT Variant Effect | deleterious(ENST00000431811); tolerated(ENST00000304166, ENST00000409489, ENST00000614107, ENST00000409363, ENST00000396211) | ||
| PolyPhen Annotation | benign; possibly_damaging | ||
| PolyPhen Variant Effect | benign(ENST00000431811, ENST00000304166); possibly_damaging(ENST00000409489, ENST00000614107, ENST00000409363, ENST00000396211) | ||
| rSNP? | No Link in rVarBase | ||
| Related Regulatory Elements | n/a | ||
| Chromatin State | Inactive region | ||
| No. of Marker's Association Results | 1 (Positive: 1; Negative: 0; Trend: 0) | ||
| Source | Literature | ||
SNP related association results
| Reference | Phenotype | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|
| Nievergelt, C. M.,2015 | PTSD | In 2179 MRS subjects of European descent: P-value=0.017. In 2179 MRS subjects of European descent: P-value=0.017. | P-value is nominally significant (P-value<0.05). P-value is nominally significant (P-value<0.05). | Significant |
G*E study related association result (count: 1)
| Reference | Phenotype | Environment | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|---|
| Nievergelt, C. M.,2015 | PTSD | Childhood trauma | In 2179 MRS subjects of European descent, gene and childhood...... In 2179 MRS subjects of European descent, gene and childhood trauma interaction: P-value<0.05. More... | It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... | Non-significant |
SNP related genes (count: 1)
| Approved Symbol | Approved Name | Location | No. of Association Results (Positive/Negative/Trend)  |
|---|---|---|---|
| ADCYAP1R1 | adenylate cyclase activating polypeptide 1 (pituitary) receptor type I | 7p14.3 | 19(8/11/0) |
SNPs in LD with rs6968349 (count: 0)
SNP related eQTL (count: 1)