PTSDgene database

SNP Report

Basic Info
Name rs138384996 dbSNP Ensembl
Location 1:64259023 - 64259023(+)
Variant Seq A
Ancestral Allele G
Ref Seq G
Minor Allele Frequence 0.0061901
Annotation intron_variant
Variant Effect intron_variant(ENST00000371077, ENST00000611228, ENST00000608956, ENST00000608020)
SIFT Annotation tolerated
SIFT Variant Effect tolerated(ENST00000611228, ENST00000608020, ENST00000608956)
PolyPhen Annotation benign
PolyPhen Variant Effect benign(ENST00000611228, ENST00000608020, ENST00000608956)
rSNP? No Link in rVarBase
Related Regulatory Elements n/a
Chromatin State Inactive region
No. of Marker's Association Results 1 (Positive: 0; Negative: 0; Trend: 1)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Nievergelt, C. M.,2015 PTSD In meta-analysis: P-value=4.1E-07. In meta-analysis: P-value=4.1E-07. It met the threshold for suggestive evidence of association ...... It met the threshold for suggestive evidence of association (P-value<5E-06). More... Trend
G*E study related association result (count: 1)
Reference Phenotype Environment Statistical Values Author Comments Marker's Category
Nievergelt, C. M.,2015 PTSD Childhood trauma Gene and childhood trauma interaction: P-value<0.05 in any s...... Gene and childhood trauma interaction: P-value<0.05 in any subjects. More... It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant


SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
UBE2U ubiquitin conjugating enzyme E2U (putative) 1p31.3 1(0/0/1)

SNPs in LD with rs138384996 (count: 0)

SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
CRHR1 Yes Adipose Subcutaneous cis GTEx