SNP Report
Basic Info
| Name | rs2471320 dbSNP Ensembl | ||
|---|---|---|---|
| Location | 7:140215320 - 140215320(+) | ||
| Variant Seq | C | ||
| Ancestral Allele | T | ||
| Ref Seq | T | ||
| Minor Allele Frequence | 0.0197684 | ||
| Annotation | downstream_gene_variant | ||
| SIFT Annotation | tolerated | ||
| SIFT Variant Effect | tolerated(ENST00000397560) | ||
| PolyPhen Annotation | possibly_damaging | ||
| PolyPhen Variant Effect | possibly_damaging(ENST00000397560) | ||
| rSNP? | Yes Link in rVarBase | ||
| Related Regulatory Elements | n/a | ||
| Chromatin State | Weak transcription;Enhancers;ZNF genes & repeats;Bivalent Enhancer | ||
| No. of Marker's Association Results | 1 (Positive: 0; Negative: 0; Trend: 1) | ||
| Source | Literature | ||
SNP related association results
| Reference | Phenotype | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|
| Nievergelt, C. M.,2015 | PTSD | In meta-analysis: P-value=4.2E-06. In meta-analysis: P-value=4.2E-06. | It met the threshold for suggestive evidence of association ...... It met the threshold for suggestive evidence of association (P-value<5E-06). More... | Trend |
G*E study related association result (count: 1)
| Reference | Phenotype | Environment | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|---|
| Nievergelt, C. M.,2015 | PTSD | Childhood trauma | In subjects of African, gene and childhood trauma interactio...... In subjects of African, gene and childhood trauma interaction: P-value=0.003. More... | It showed a significant interaction effect with childhood tr...... It showed a significant interaction effect with childhood trauma on PTSD. More... | Significant |
SNP related genes (count: 1)
| Approved Symbol | Approved Name | Location | No. of Association Results (Positive/Negative/Trend)  |
|---|---|---|---|
| JHDM1D-AS1 | JHDM1D antisense RNA 1 (head to head) | 7q34 | 1(0/0/1) |
SNPs in LD with rs2471320 (count: 0)
SNP related eQTL (count: 1)