SNP Report
Basic Info
| Name | rs4659395 dbSNP Ensembl | ||
|---|---|---|---|
| Location | 1:25891774 - 25891774(+) | ||
| Variant Seq | G | ||
| Ancestral Allele | A | ||
| Ref Seq | A | ||
| Minor Allele Frequence | 0.0147764 | ||
| Annotation | downstream_gene_variant; intron_variant; non_coding_transcript_variant | ||
| Variant Effect | downstream_gene_variant(ENST00000440710, ENST00000453780); intron_variant(ENST00000426559, ENST00000513116); non_coding_transcript_variant(ENST00000513116) | ||
| SIFT Annotation | tolerated_-_low_confidence | ||
| SIFT Variant Effect | tolerated_-_low_confidence(ENST00000426559) | ||
| PolyPhen Annotation | benign | ||
| PolyPhen Variant Effect | benign(ENST00000426559) | ||
| rSNP? | Yes Link in rVarBase | ||
| Related Regulatory Elements | Chromatin interactive region | ||
| Chromatin State | Enhancers;Weak transcription;Strong transcription;Flanking Active TSS;Genic enhancers | ||
| No. of Marker's Association Results | 1 (Positive: 0; Negative: 1; Trend: 0) | ||
| Source | Literature | ||
SNP related association results
| Reference | Phenotype | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|
| Nievergelt, C. M.,2015 | PTSD | In 2179 MRS subjects of European descent: P-value=0.09. In 2179 MRS subjects of European descent: P-value=0.09. | No significant result. No significant result. | Non-significant |
G*E study related association result (count: 1)
| Reference | Phenotype | Environment | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|---|
| Nievergelt, C. M.,2015 | PTSD | Childhood trauma | In 2179 MRS subjects of European descent, gene and childhood...... In 2179 MRS subjects of European descent, gene and childhood trauma interaction: P-value<0.05. More... | It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... | Non-significant |
SNP related genes (count: 4)
| Approved Symbol | Approved Name | Location | No. of Association Results (Positive/Negative/Trend)  |
|---|---|---|---|
| SNRPFP2 | small nuclear ribonucleoprotein polypeptide F pseudogene 2 | 1p36.11 | Mapped by Literature SNP, Mapped by LD-proxy, rSNP target |
| MTFR1L | mitochondrial fission regulator 1-like | 1p36.11 | rSNP target |
| PAFAH2 | platelet-activating factor acetylhydrolase 2 | 1p34.3 | Mapped by LD-proxy, rSNP target |
| STMN1 | stathmin 1 | 1p36.11 | 6(1/5/0) |
SNPs in LD with rs4659395 (count: 1)
Literature-origin SNPs (count: 0)
LD-proxies (count: 1)
SNP related eQTL (count: 1)