PTSDgene database

Gene Report

Basic Info
Approved Symbol CRHR1
Previous Symbol CRHR
Symbol Alias "CRF-R|CRF1"
Approved Name corticotropin releasing hormone receptor 1
Name Alias corticotropin-releasing factor receptor
Location 17q21.31
Position chr17:45784280-45835828, 1
External Links HGNC: 2357
Entrez Gene: 1394
Ensembl: ENSG00000120088
UCSC: uc002ijm.3
No. of Association Results 12 (Positive: 6; Negative: 6; trend: 0)
Annotation Type Literature-origin, Mapped by Literature SNP, Mapped by LD-proxy, rSNP target
Gene related association results
Normal genetic study related association results (count: 12)
Reference Phenotype Marker Gene's Category
Amstadter, A. B.,2011 Acute symptoms of PTSD rs12944712 Significant
Amstadter, A. B.,2011 Acute UCLA PTSD-RI score rs12936181 ; rs12944712 ; rs17690314 ; rs17763104 ; rs17763658 ; rs2424942 ; rs4074461 ; rs4458044 Significant
Amstadter, A. B.,2011 Decline in PTSD symptoms rs12944712 Significant
Dunn, E. C.,2014 Post Traumatic Growth (PTG) rs12944712 Non-significant
White, S.,2013 Post-hurricane PTSD diagnosis rs12938031 ; rs4792887 Significant
White, S.,2013 Post-hurricane PTSD symptoms rs110402 ; rs12938031 ; rs16940686 ; rs171441 ; rs173365 ; rs17689966 ; rs242924 ; rs242936 ; rs242939 ; rs2664008 ; rs4792887 ; rs7209436 Significant
Davydow, D. S.,2014 Post-ICU PTSD rs1876831 Non-significant
Dunn, E. C.,2014 Post-traumatic stress symptoms (PTS) rs12944712 Non-significant
Nievergelt, C. M.,2015 PTSD rs116897693 Significant
Solovieff, N.,2014 PTSD diagnosis rs242941 Non-significant
Solovieff, N.,2014 PTSD severity rs242941 Non-significant
Binder, E. B.,2008 PTSD symptom severity rs110402 ; rs242924 ; rs7209436 Non-significant
G*E study related association result (count: 1)
Reference Phenotype Environment Marker Gene's Category
Dunn, E. C.,2014 Post Traumatic Growth (PTG) Hurricane exposure rs12944712 ; rs116897693 ; rs110402 ; rs242924 ; rs7209436 Non-significant
Gene functional annotation
Gene related GO terms (count: 18)

Gene related KEGG pathways (count: 2)

Gene related interactors from protein-protein interactions data in PINA v2 (count: 7)