PTSDgene database

Gene Report

Basic Info
Approved Symbol APOE
Previous Symbol AD2
Approved Name apolipoprotein E
Previous Name Alzheimer disease 2 (APOE*E4-associated, late onset)
Location 19q13.31
Position chr19:44905754-44909393, 1
External Links HGNC: 613
Entrez Gene: 348
Ensembl: ENSG00000130203
UCSC: uc002pab.3
No. of Association Results 6 (Positive: 2; Negative: 4; trend: 0)
Annotation Type Literature-origin, Mapped by Literature SNP, Mapped by LD-proxy, rSNP target
Gene related association results
Normal genetic study related association results (count: 6)
Reference Phenotype Marker Gene's Category
Kim, T. Y.,2013 PTSD APOE_euro2/euro3/euro4 Significant
Lyons, M. J.,2013 PTSD diagnosis APOE_euro4 Non-significant
Lyons, M. J.,2013 PTSD symptomatology APOE_euro4 Significant
Nievergelt, C. M.,2015 PTSD rs1081105 Non-significant
Solovieff, N.,2014 PTSD diagnosis rs584007 Non-significant
Solovieff, N.,2014 PTSD severity rs584007 Non-significant
G*E study related association result (count: 1)
Reference Phenotype Environment Marker Gene's Category
Lyons, M. J.,2013 Diagnosis of PTSD Combat exposure APOE_euro4 ; rs1081105 ; APOE_euro2/euro3/euro4 Significant
Gene functional annotation
Gene related GO terms (count: 126)

Gene related KEGG pathways (count: 2)

Gene related interactors from protein-protein interactions data in PINA v2 (count: 56)