Gene Report

Basic Info

Approved Symbol	RGS7
Approved Name	regulator of G-protein signaling 7
Previous Name	regulator of G-protein signalling 7
Location	1q43
Position	chr1:240775515-241357230, -1
External Links	HGNC: 10003 Entrez Gene: 6000 Ensembl: ENSG00000182901 UCSC: uc001hyv.3
No. of Association Results	1 (Positive: 0; Negative: 0; trend: 1)
Annotation Type	Literature-origin, Mapped by Literature SNP, Mapped by LD-proxy

Gene related association results

Normal genetic study related association results (count: 1)

Reference	Phenotype	Marker	Gene's Category
Nievergelt, C. M.,2015	PTSD	rs10737854	Trend

G*E study related association result (count: 1)

Reference	Phenotype	Environment	Marker	Gene's Category
Nievergelt, C. M.,2015	PTSD	Childhood trauma	rs10737854	Non-significant

Gene functional annotation

Gene related GO terms (count: 14)

ID	Name	Type	Evidence[PMID]	No. of Genes in PTSDgene
GO:0008277	regulation of G-protein coupled receptor protein signaling pathway	biological process	IEA	3
GO:0004871	signal transducer activity	molecular function	IEA	5
GO:0005886	plasma membrane	cellular component	IBA	99
GO:0005096	GTPase activator activity	molecular function	IBA; IDA[10521509]	9
GO:0005829	cytosol	cellular component	IDA[10521509]	78
GO:0005634	nucleus	cellular component	IEA	81
GO:0005834	heterotrimeric G-protein complex	cellular component	IEA	2
GO:0035556	intracellular signal transduction	biological process	IEA	10
GO:0009968	negative regulation of signal transduction	biological process	IEA	1
GO:0005737	cytoplasm	cellular component	IBA	109
GO:0007186	G-protein coupled receptor signaling pathway	biological process	IEA	14
GO:0031681	G-protein beta-subunit binding	molecular function	IPI[19376773]	1
GO:0043547	positive regulation of GTPase activity	biological process	IDA[10521509]	13
GO:0044292	dendrite terminus	cellular component	IEA	1

Gene related KEGG pathways (count: 0)

Gene related interactors from protein-protein interactions data in PINA v2 (count: 3)

Gene	Interactor	Interactor in PTSDgene?	Experiment Method	Interaction Type	PMID
RGS7	GNAI1	No	--	--	9572280
RGS7	PKD1	No	--	--	10339594 , 10339594 , 10339594 , 10339594
RGS7	GNAQ	No	--	--	12670932 , 12670932