PTSDgene database

Gene Report

Basic Info
Approved Symbol TPH1
Previous Symbol "TPRH|TPH"
Approved Name tryptophan hydroxylase 1
Previous Name tryptophan hydroxylase (tryptophan 5-monooxygenase)
Name Alias tryptophan 5-monooxygenase
Location 11p15.3-p14
Position chr11:18017564-18042426, -1
External Links HGNC: 12008
Entrez Gene: 7166
Ensembl: ENSG00000129167
UCSC: uc001mnp.2
No. of Association Results 5 (Positive: 1; Negative: 4; trend: 0)
Annotation Type Literature-origin, Mapped by Literature SNP, Mapped by LD-proxy, rSNP target
Gene related association results
Normal genetic study related association results (count: 5)
Reference Phenotype Marker Gene's Category
Nelson, E. C.,2014 PTSD rs17794760 Non-significant
Nievergelt, C. M.,2015 PTSD rs544437 Non-significant
Solovieff, N.,2014 PTSD diagnosis rs11606304 Non-significant
Solovieff, N.,2014 PTSD severity rs11606304 Non-significant
Goenjian, A. K.,2012 PTSD-RI (PTSD symptoms) rs1799913 ; rs2108977 Significant
G*E study related association result (count: 1)
Reference Phenotype Environment Marker Gene's Category
Nievergelt, C. M.,2015 PTSD Childhood trauma rs544437 Non-significant
Gene functional annotation
Gene related GO terms (count: 17)

Gene related KEGG pathways (count: 1)

Gene related interactors from protein-protein interactions data in PINA v2 (count: 2)