SNP Report
Basic Info
| Name | rs79590198 dbSNP Ensembl | ||
|---|---|---|---|
| Location | 5:143307371 - 143307371(+) | ||
| Variant Seq | A | ||
| Ancestral Allele | G | ||
| Ref Seq | G | ||
| Minor Allele Frequence | 0.0509185 | ||
| Annotation | intron_variant; non_coding_transcript_variant | ||
| Variant Effect | intron_variant(ENST00000503201, ENST00000504336, ENST00000504572, ENST00000394464, ENST00000343796, ENST00000424646, ENST00000231509, ENST00000394466, ENST00000415690); non_coding_transcript_variant(ENST00000504336) | ||
| SIFT Annotation | deleterious | ||
| SIFT Variant Effect | deleterious(ENST00000394464, ENST00000503201, ENST00000415690, ENST00000424646, ENST00000231509, ENST00000343796, ENST00000504572, ENST00000394466) | ||
| PolyPhen Annotation | probably_damaging | ||
| PolyPhen Variant Effect | probably_damaging(ENST00000394464, ENST00000503201, ENST00000415690, ENST00000424646, ENST00000231509, ENST00000343796, ENST00000504572, ENST00000394466) | ||
| rSNP? | Yes Link in rVarBase | ||
| Related Regulatory Elements | n/a | ||
| Chromatin State | Weak transcription;Strong transcription;ZNF genes & repeats | ||
| No. of Marker's Association Results | 1 (Positive: 0; Negative: 1; Trend: 0) | ||
| Source | Literature | ||
SNP related association results
| Reference | Phenotype | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|
| Nievergelt, C. M.,2015 | PTSD | In 2179 MRS subjects of European descent: P-value=0.09. In 2179 MRS subjects of European descent: P-value=0.09. | No significant result. No significant result. | Non-significant |
G*E study related association result (count: 1)
| Reference | Phenotype | Environment | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|---|
| Nievergelt, C. M.,2015 | PTSD | Childhood trauma | In 2179 MRS subjects of European descent, gene and childhood...... In 2179 MRS subjects of European descent, gene and childhood trauma interaction: P-value=0.022. More... | It showed a significant interaction effect with childhood tr...... It showed a significant interaction effect with childhood trauma on PTSD. More... | Significant |
SNP related genes (count: 1)
| Approved Symbol | Approved Name | Location | No. of Association Results (Positive/Negative/Trend)  |
|---|---|---|---|
| NR3C1 | nuclear receptor subfamily 3 group C member 1 | 5q31-q32 | 6(2/4/0) |
SNPs in LD with rs79590198 (count: 0)
SNP related eQTL (count: 1)