PTSDgene database

SNP Report

Basic Info
Name rs141129523 dbSNP Ensembl
Location 1:192814167 - 192814167(+)
Variant Seq G
Ancestral Allele A
Ref Seq A
Minor Allele Frequence 0.0119808
Annotation downstream_gene_variant
Variant Effect downstream_gene_variant(ENST00000464302, ENST00000487236, ENST00000235382, ENST00000483295)
SIFT Annotation tolerated
SIFT Variant Effect tolerated(ENST00000235382)
PolyPhen Annotation possibly_damaging
PolyPhen Variant Effect possibly_damaging(ENST00000235382)
rSNP? Yes Link in rVarBase
Related Regulatory Elements Chromatin interactive region
Chromatin State Weak transcription;Enhancers;Flanking Active TSS
No. of Marker's Association Results 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Nievergelt, C. M.,2015 PTSD In 2179 MRS subjects of European descent: P-value=0.022. In 2179 MRS subjects of European descent: P-value=0.022. P-value is nominally significant (P-value<0.05). P-value is nominally significant (P-value<0.05). Significant
G*E study related association result (count: 1)
Reference Phenotype Environment Statistical Values Author Comments Marker's Category
Nievergelt, C. M.,2015 PTSD Childhood trauma In 2179 MRS subjects of European descent, gene and childhood...... In 2179 MRS subjects of European descent, gene and childhood trauma interaction: P-value<0.05. More... It showed a non-significant interaction effect with childhoo...... It showed a non-significant interaction effect with childhood trauma on PTSD. More... Non-significant


SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
RGS2 regulator of G-protein signaling 2 1q31 7(2/5/0)

SNPs in LD with rs141129523 (count: 0)

SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
WNT3 No Adipose Subcutaneous cis GTEx