Gene Report

Basic Info

Approved Symbol	LGR6
Symbol Alias	FLJ14471
Approved Name	leucine-rich repeat containing G protein-coupled receptor 6
Previous Name	leucine-rich repeat-containing G protein-coupled receptor 6
Location	1q32.1
Position	chr1:202193901-202319781, 1
External Links	HGNC: 19719 Entrez Gene: 59352 Ensembl: ENSG00000133067 UCSC: uc001gxu.3
No. of Association Results	1 (Positive: 0; Negative: 0; trend: 1)
Annotation Type	Literature-origin, Mapped by Literature SNP, Mapped by LD-proxy

Gene related association results

Normal genetic study related association results (count: 1)

Reference	Phenotype	Marker	Gene's Category
Nievergelt, C. M.,2015	PTSD	rs3100127	Trend

G*E study related association result (count: 1)

Reference	Phenotype	Environment	Marker	Gene's Category
Nievergelt, C. M.,2015	PTSD	Childhood trauma	rs3100127	Non-significant

Gene functional annotation

Gene related GO terms (count: 12)

ID	Name	Type	Evidence[PMID]	No. of Genes in PTSDgene
GO:0005886	plasma membrane	cellular component	TAS	99
GO:0016055	Wnt signaling pathway	biological process	IEA	3
GO:0007186	G-protein coupled receptor signaling pathway	biological process	IEA	14
GO:0030335	positive regulation of cell migration	biological process	IDA[22615920]	3
GO:0004888	transmembrane signaling receptor activity	molecular function	ISS	2
GO:0004930	G-protein coupled receptor activity	molecular function	ISS	7
GO:0090263	positive regulation of canonical Wnt signaling pathway	biological process	ISS	2
GO:0005515	protein binding	molecular function	IPI[21727895\|22615920]	169
GO:0032588	trans-Golgi network membrane	cellular component	ISS	2
GO:0030177	positive regulation of Wnt signaling pathway	biological process	IDA[22615920]	2
GO:0005887	integral component of plasma membrane	cellular component	ISS	36
GO:0031982	vesicle	cellular component	IDA[22615920]	7

Gene related KEGG pathways (count: 0)

Gene related interactors from protein-protein interactions data in PINA v2 (count: 0)