
Gene Report
Approved Symbol | DRD4 |
---|---|
Approved Name | dopamine receptor D4 |
Location | 11p15.5 |
Position | chr11:637293-640706, 1 |
External Links |
HGNC: 3025 Entrez Gene: 1815 Ensembl: ENSG00000069696 UCSC: uc001lqp.2 |
No. of Association Results | 7 (Positive: 2; Negative: 5; trend: 0) |
Annotation Type | Literature-origin, Mapped by Literature SNP |
Reference | Phenotype | Marker | Gene's Category |
---|---|---|---|
Dragan, W. L.,2009 | Avoidance/Numbing symptoms | DRD4_exon3_VNTR | Significant |
Dragan, W. L.,2009 | Intrusion/Arousal symptoms | DRD4_exon3_VNTR | Non-significant |
Dragan, W. L.,2009 | PTSD-C score | DRD4_exon3_VNTR | Significant |
Dragan, W. L.,2009 | PTSD-F score | DRD4_exon3_VNTR | Non-significant |
Nievergelt, C. M.,2015 | PTSD | rs4987059 | Non-significant |
Solovieff, N.,2014 | PTSD diagnosis | rs7126715 | Non-significant |
Solovieff, N.,2014 | PTSD severity | rs752306 | Non-significant |
Reference | Phenotype | Environment | Marker | Gene's Category |
---|---|---|---|---|
Nievergelt, C. M.,2015 | PTSD | Childhood trauma | rs4987059 | Non-significant |
ID | Name | No. of Genes in PTSDgene |
---|---|---|
hsa04080 | Neuroactive ligand-receptor interaction | 22 |
Gene | Interactor | Interactor in PTSDgene? | Experiment Method | Interaction Type | PMID |
---|---|---|---|---|---|
DRD4 | KCNJ5 | No | -- | -- | 12297500 |
DRD4 | KCNJ3 | No | -- | -- | 12297500 |
DRD4 | CLIC6 | No | -- | -- | 14499480 , 14499480 |
DRD4 | ARRB2 | No | -- | -- | 20100572 |
DRD4 | KCNJ9 | No | -- | -- | 12297500 , 12297500 |
DRD4 | KLHL12 | No | -- | -- | 18303015 , 20100572 , 20100572 |
DRD4 | GRB2 | No | -- | -- | 9843378 , 9843378 |
DRD4 | STUB1 | No | -- | -- | 20974815 |
Copyright: Key Lab of Mental Health, Institute of Psychology, Chinese Academy of Sciences Feedback
Last update: April 1, 2018