PTSDgene database

SNP Report

Basic Info
Name rs17690314 dbSNP Ensembl
Location 17:45842518 - 45842518(+)
Variant Seq G
Ancestral Allele G
Ref Seq T
Minor Allele Frequence 0.0860623
Annotation downstream_gene_variant; upstream_gene_variant; intron_variant; non_coding_transcript_variant
Variant Effect downstream_gene_variant(ENST00000579599, ENST00000579244, ENST00000581125); upstream_gene_variant(ENST00000329196); intron_variant(ENST00000634876); non_coding_transcript_variant(ENST00000634876)
SIFT Annotation deleterious
SIFT Variant Effect deleterious(ENST00000329196)
PolyPhen Annotation probably_damaging
PolyPhen Variant Effect probably_damaging(ENST00000329196)
rSNP? Yes Link in rVarBase
Related Regulatory Elements n/a
Chromatin State Weak transcription;Enhancers
No. of Marker's Association Results 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Amstadter, A. B.,2011 Acute UCLA PTSD-RI score B=-5.41, t=-1.87, Empirical P-value=0.08 B=-5.41, t=-1.87, Empirical P-value=0.08 No significant result. No significant result. Non-significant


SNP related genes (count: 3)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
CRHR1 corticotropin releasing hormone receptor 1 17q21.31 12(6/6/0)
SPPL2C signal peptide peptidase like 2C 17q21.31 Mapped by Literature SNP, Mapped by LD-proxy, rSNP target
MAPT-AS1 MAPT antisense RNA 1 17q21.31 Mapped by Literature SNP, Mapped by LD-proxy, rSNP target

SNPs in LD with rs17690314 (count: 935)
The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 1)

LD-proxies (count: 934)