SNP Report
Basic Info
| Name | rs7131056 dbSNP Ensembl | ||
|---|---|---|---|
| Location | 11:113459052 - 113459052(+) | ||
| Variant Seq | C | ||
| Ancestral Allele | C | ||
| Ref Seq | A | ||
| Minor Allele Frequence | 0.499401 | ||
| Annotation | intron_variant; non_coding_transcript_variant | ||
| Variant Effect | intron_variant(ENST00000346454, ENST00000540600, ENST00000362072, ENST00000542616); non_coding_transcript_variant(ENST00000540600) | ||
| SIFT Annotation | tolerated | ||
| SIFT Variant Effect | tolerated(ENST00000362072, ENST00000543292, ENST00000538967, ENST00000544518, ENST00000542968, ENST00000346454) | ||
| PolyPhen Annotation | benign | ||
| PolyPhen Variant Effect | benign(ENST00000362072, ENST00000543292, ENST00000538967, ENST00000544518, ENST00000542968, ENST00000346454) | ||
| rSNP? | Yes Link in rVarBase | ||
| Related Regulatory Elements | n/a | ||
| Chromatin State | Weak transcription | ||
| No. of Marker's Association Results | 1 (Positive: 1; Negative: 0; Trend: 0) | ||
| Source | Literature | ||
SNP related association results
| Reference | Phenotype | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|
| Duan, Z.,2015 | PTSD diagnosis | Allele dose analysis model: P-value=0.04; Dominant effect: ...... Allele dose analysis model: P-value=0.04; Dominant effect: P-value=0.02; Recessive effect: P-value=0.18 More... | Rs7131056 was significantly associated with the risk of PTSD...... Rs7131056 was significantly associated with the risk of PTSD in all allele dose analysis models, in dominant effect, compared with rs7131056 CC genotypes, the combined genotypes rs7131056 AA/AC had a significantly increased PTSD risk. More... | Significant |
SNP related genes (count: 1)
| Approved Symbol | Approved Name | Location | No. of Association Results (Positive/Negative/Trend)  |
|---|---|---|---|
| DRD2 | dopamine receptor D2 | 11q23.2 | 18(11/7/0) |
SNPs in LD with rs7131056 (count: 0)
SNP related eQTL (count: 1)