PTSDgene database

SNP Report

Basic Info
Name rs12805897 dbSNP Ensembl
Location 11:113453571 - 113453571(+)
Variant Seq A
Ancestral Allele G
Ref Seq G
Minor Allele Frequence 0.0493211
Annotation upstream_gene_variant; intron_variant; non_coding_transcript_variant
Variant Effect upstream_gene_variant(ENST00000577203); intron_variant(ENST00000542616, ENST00000346454, ENST00000540600, ENST00000362072); non_coding_transcript_variant(ENST00000540600)
SIFT Annotation tolerated
SIFT Variant Effect tolerated(ENST00000362072, ENST00000543292, ENST00000538967, ENST00000544518, ENST00000542968, ENST00000346454)
PolyPhen Annotation benign
PolyPhen Variant Effect benign(ENST00000362072, ENST00000543292, ENST00000538967, ENST00000544518, ENST00000542968, ENST00000346454)
rSNP? Yes Link in rVarBase
Related Regulatory Elements n/a
Chromatin State Weak transcription
No. of Marker's Association Results 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Nelson, E. C.,2014 PTSD P-value=0.00029, OR=1.63 P-value=0.00029, OR=1.63 The association observed for rs12805897 is likely due to its...... The association observed for rs12805897 is likely due to its high linkage disequilibrium with rs12364283. More... Non-significant


SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
MIR4301 microRNA 4301 11 Mapped by Literature SNP, Mapped by LD-proxy
DRD2 dopamine receptor D2 11q23.2 18(11/7/0)

SNPs in LD with rs12805897 (count: 2)
The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 1)

LD-proxies (count: 1)


SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
TMPRSS5 No Adipose Subcutaneous cis GTEx