PTSDgene database

SNP Report

Basic Info
Name rs4648318 dbSNP Ensembl
Location 11:113442667 - 113442667(+)
Variant Seq C
Ancestral Allele T
Ref Seq T
Minor Allele Frequence 0.41893
Annotation intron_variant; non_coding_transcript_variant
Variant Effect intron_variant(ENST00000543292, ENST00000542616, ENST00000362072, ENST00000346454, ENST00000540600); non_coding_transcript_variant(ENST00000540600)
SIFT Annotation tolerated
SIFT Variant Effect tolerated(ENST00000362072, ENST00000543292, ENST00000538967, ENST00000544518, ENST00000542968, ENST00000346454)
PolyPhen Annotation benign
PolyPhen Variant Effect benign(ENST00000362072, ENST00000543292, ENST00000538967, ENST00000544518, ENST00000542968, ENST00000346454)
rSNP? Yes Link in rVarBase
Related Regulatory Elements Chromatin interactive region
Chromatin State Enhancers;Weak transcription
No. of Marker's Association Results 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Duan, Z.,2015 PTSD diagnosis Allele dose analysis model: P-value=0.42; Dominant effect: ...... Allele dose analysis model: P-value=0.42; Dominant effect: P-value=1.00; Recessive effect: P-value=0.23. More... No significant results. No significant results. Non-significant


SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
DRD2 dopamine receptor D2 11q23.2 18(11/7/0)

SNPs in LD with rs4648318 (count: 2)
The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 1)

LD-proxies (count: 1)


SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
TMPRSS5 No Adipose Subcutaneous cis GTEx