PTSDgene database

SNP Report

Basic Info
Name rs1124492 dbSNP Ensembl
Location 11:113411553 - 113411553(+)
Variant Seq A
Ancestral Allele C
Ref Seq C
Minor Allele Frequence 0.29992
Annotation downstream_gene_variant; non_coding_transcript_exon_variant; intron_variant; non_coding_transcript_variant
Variant Effect downstream_gene_variant(ENST00000539420, ENST00000535984, ENST00000540600); non_coding_transcript_exon_variant(ENST00000546284); intron_variant(ENST00000544518, ENST00000542968, ENST00000346454, ENST00000538967, ENST00000362072); non_coding_transcript_variant(ENST00000546284)
SIFT Annotation tolerated
SIFT Variant Effect tolerated(ENST00000542968, ENST00000346454, ENST00000538967, ENST00000362072, ENST00000544518)
PolyPhen Annotation benign
PolyPhen Variant Effect benign(ENST00000542968, ENST00000346454, ENST00000538967, ENST00000362072, ENST00000544518)
rSNP? Yes Link in rVarBase
Related Regulatory Elements lncRNA
Chromatin State Weak transcription
No. of Marker's Association Results 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Solovieff, N.,2014 PTSD diagnosis P-value=0.266 P-value=0.266 Achieved nominal levels of significance with PTSD diagnosis,...... Achieved nominal levels of significance with PTSD diagnosis, although was not significant after correction for multiple testing More... Non-significant

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
DRD2 dopamine receptor D2 11q23.2 18(11/7/0)

SNPs in LD with rs1124492 (count: 9)
The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 1)

LD-proxies (count: 8)

SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
LRRC37A4P No Adipose Subcutaneous cis GTEx