PTSDgene database

Pathway Enrichment Analysis Protein-Protein Interaction Analysis

SNP Report

Basic Info

Name	rs1799732 dbSNP Ensembl
Location	11:113475529 - 113475529(+)
Variant Seq	G
Ref Seq	-
Minor Allele Frequence	0.241613
Annotation	upstream_gene_variant; intron_variant; non_coding_transcript_variant
Variant Effect	upstream_gene_variant(ENST00000542616, ENST00000362072, ENST00000346454); intron_variant(ENST00000540600); non_coding_transcript_variant(ENST00000540600)
SIFT Annotation	tolerated
SIFT Variant Effect	tolerated(ENST00000362072, ENST00000543292, ENST00000538967, ENST00000544518, ENST00000542968, ENST00000346454)
PolyPhen Annotation	benign
PolyPhen Variant Effect	benign(ENST00000362072, ENST00000543292, ENST00000538967, ENST00000544518, ENST00000542968, ENST00000346454)
rSNP?	Yes Link in rVarBase
Related Regulatory Elements	TF binding region;CpG island
Chromatin State	Bivalent/Poised TSS;Flanking Bivalent TSS/Enh;Bivalent Enhancer;Active TSS;Flanking Active TSS;Enhancers
No. of Marker's Association Results	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature

SNP related association results

Normal genetic study related association results (count: 1)

Reference	Phenotype	Statistical Values	Author Comments	Marker's Category
Voisey, J.,2009	PTSD	Allele frequencies: X²= 0.71, P-value= 0.40, Odd...... Allele frequencies: X²= 0.71, P-value= 0.40, Odd's ratio (95% CI): 0.78(0.42-1.42), Genotype frequencies: Likelihood-ratio chi-square test: X²= 0.74, P-value= 0.691 More...	No association with PTSD was observed for rs1799732 polymorp...... No association with PTSD was observed for rs1799732 polymorphisms at the allele or genotype level. More...	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Association Results (Positive/Negative/Trend)
DRD2	dopamine receptor D2	11q23.2	18(11/7/0)

SNPs in LD with rs1799732 (count: 0)

SNP related eQTL (count: 1)

Gene Symbol	Gene Existed in PTSDgene?	Tissue	Trans/Cis	Source
TRIM37	Yes	Adipose Subcutaneous	cis	GTEx