PTSDgene database

Study Report

Study Information
Basic Info
Reference
Citation Bailey, J. N., et al. (2010). "PTSD and dopaminergic genes, DRD2 and DAT, in multigenerational families exposed to the Spitak earthquake." Psychiatry Res 178(3): 507-510.
Phenotype PTSD diagnosis, PTSD symptoms and PTSD category B symptom score, PTSD category C symptom score
Trauma 1988 Spitak earthquake
Study Design Cross-sectional study
Study Type Candidate gene association study
Sample Size 200 samples
SNP/Marker Size 1 SNP,1 Variant
Predominant Ethnicity Caucasian
Population Caucasian Armenian
Gender 121 females, 79 males
Age Not mentioned

Detail Info

Genetic result reported by this study
Normal genetic result reported by this study (count: 8)
Marker Phenotype Related Gene Statistical Values Author Comments Marker's Category
rs1800497 PTSD category B symptom score DRD2 B=0.62, P-value=0.61 There was no association between DRD2/A1+ allele and PTSD ca...... There was no association between DRD2/A1+ allele and PTSD category B symptom score. More... Non-significant
rs1800497 PTSD category C symptom score DRD2 B=1.28, P-value=0.39 There was no association between DRD2/A1+ allele and PTSD ca...... There was no association between DRD2/A1+ allele and PTSD category C symptom score. More... Non-significant
DAT_3'UTR_VNTR PTSD symptoms SLC6A3 B=-1.14, P-value=0.87 There was no association between DAT/9 repeat allele and PTS...... There was no association between DAT/9 repeat allele and PTSD diagnosis. More... Non-significant
rs1800497 PTSD diagnosis DRD2 X2=0.35, P-value=0.56, after controlling for alcohol dependency: B=?3.36, P-value=0.44 There was no association between DRD2/A1+ allele and PTSD di...... There was no association between DRD2/A1+ allele and PTSD diagnosis. More... Non-significant
DAT_3'UTR_VNTR PTSD diagnosis SLC6A3 X2=2.6, P-value=0.11, after controlling for alcohol dependency: B=?2.44, P-value=0.65 There was no association between DAT/9 repeat allele and PTS...... There was no association between DAT/9 repeat allele and PTSD diagnosis. More... Non-significant
rs1800497 PTSD symptoms DRD2 B=1.92, P-value=0.44 There was no association between DRD2/A1+ allele and total P...... There was no association between DRD2/A1+ allele and total PTSD-RI scores. More... Non-significant
DAT_3'UTR_VNTR PTSD category B symptom score SLC6A3 B=-1.23, P-value=0.35 There was no association between DAT/9 repeat allele and PTS...... There was no association between DAT/9 repeat allele and PTSD diagnosis. More... Non-significant
DAT_3'UTR_VNTR PTSD category C symptom score SLC6A3 B=-0.50, P-value=0.72 There was no association between DAT/9 repeat allele and PTS...... There was no association between DAT/9 repeat allele and PTSD diagnosis. More... Non-significant