SNP Report
Basic Info
| Name | rs2734833 dbSNP Ensembl | ||
|---|---|---|---|
| Location | 11:113422198 - 113422198(+) | ||
| Variant Seq | A | ||
| Ancestral Allele | G | ||
| Ref Seq | G | ||
| Minor Allele Frequence | 0.313299 | ||
| Annotation | downstream_gene_variant; upstream_gene_variant; intron_variant; non_coding_transcript_variant | ||
| Variant Effect | downstream_gene_variant(ENST00000542616); upstream_gene_variant(ENST00000539420); intron_variant(ENST00000543292, ENST00000544518, ENST00000346454, ENST00000535984, ENST00000362072, ENST00000542968, ENST00000538967, ENST00000540600); non_coding_transcript_variant(ENST00000535984, ENST00000540600) | ||
| SIFT Annotation | deleterious_-_low_confidence; deleterious | ||
| SIFT Variant Effect | deleterious_-_low_confidence(ENST00000362072, ENST00000544518, ENST00000542968); deleterious(ENST00000538967, ENST00000346454, ENST00000543292) | ||
| PolyPhen Annotation | benign; possibly_damaging | ||
| PolyPhen Variant Effect | benign(ENST00000362072, ENST00000346454, ENST00000544518, ENST00000543292, ENST00000542968); possibly_damaging(ENST00000538967) | ||
| rSNP? | Yes Link in rVarBase | ||
| Related Regulatory Elements | TF binding region | ||
| Chromatin State | Weak transcription | ||
| No. of Marker's Association Results | 1 (Positive: 0; Negative: 1; Trend: 0) | ||
| Source | Literature | ||
SNP related association results
| Reference | Phenotype | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|
| Duan, Z.,2015 | PTSD diagnosis | Allele dose analysis model: P-value=0.48; Dominant effect: ...... Allele dose analysis model: P-value=0.48; Dominant effect: P-value=0.91; Recessive effect: P-value=0.52. More... | No significant results. No significant results. | Non-significant |
SNP related genes (count: 1)
| Approved Symbol | Approved Name | Location | No. of Association Results (Positive/Negative/Trend)  |
|---|---|---|---|
| DRD2 | dopamine receptor D2 | 11q23.2 | 18(11/7/0) |
SNPs in LD with rs2734833 (count: 52)
Literature-origin SNPs (count: 1)
LD-proxies (count: 51)
SNP related eQTL (count: 1)