SNP Report
Basic Info
| Name | rs12938031 dbSNP Ensembl | ||
|---|---|---|---|
| Location | 17:45777136 - 45777136(+) | ||
| Variant Seq | G | ||
| Ancestral Allele | A | ||
| Ref Seq | A | ||
| Minor Allele Frequence | 0.170727 | ||
| Annotation | intron_variant; non_coding_transcript_variant | ||
| Variant Effect | intron_variant(ENST00000587305, ENST00000634540); non_coding_transcript_variant(ENST00000587305) | ||
| SIFT Annotation | deleterious; tolerated | ||
| SIFT Variant Effect | deleterious(ENST00000430334); tolerated(ENST00000430334, ENST00000581448, ENST00000584420, ENST00000589780) | ||
| PolyPhen Annotation | benign; possibly_damaging | ||
| PolyPhen Variant Effect | benign(ENST00000430334, ENST00000581448, ENST00000584420, ENST00000589780); possibly_damaging(ENST00000430334, ENST00000584420) | ||
| rSNP? | Yes Link in rVarBase | ||
| Related Regulatory Elements | n/a | ||
| Chromatin State | Weak transcription | ||
| No. of Marker's Association Results | 2 (Positive: 2; Negative: 0; Trend: 0) | ||
| Source | Literature | ||
SNP related association results
| Reference | Phenotype | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|
| White, S.,2013 | Post-hurricane PTSD diagnosis | OR=0.58, P-value>0.05 OR=0.58, P-value>0.05 | Results indicated that rs12938031 was associated with PTSD d...... Results indicated that rs12938031 was associated with PTSD diagnosis. More... | Significant |
| White, S.,2013 | Post-hurricane PTSD symptoms | In EA sunsamples: B=-0.33, t=-0.46, P-value<0.001 In EA sunsamples: B=-0.33, t=-0.46, P-value<0.001 | Nominally associated with higher post-hurricane PTSD symptom...... Nominally associated with higher post-hurricane PTSD symptoms, after a Bonferroni adjustment for multiple testing was employed, remained significant. More... | Significant |
SNP related genes (count: 1)
| Approved Symbol | Approved Name | Location | No. of Association Results (Positive/Negative/Trend)  |
|---|---|---|---|
| CRHR1 | corticotropin releasing hormone receptor 1 | 17q21.31 | 12(6/6/0) |
SNPs in LD with rs12938031 (count: 1)
Literature-origin SNPs (count: 0)
LD-proxies (count: 1)
SNP related eQTL (count: 1)