PTSDgene database

SNP Report

Basic Info
Name rs17763104 dbSNP Ensembl
Location 17:45828429 - 45828429(+)
Variant Seq A
Ancestral Allele G
Ref Seq G
Minor Allele Frequence 0.0672923
Annotation upstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant
Variant Effect upstream_gene_variant(ENST00000581479, ENST00000535778, ENST00000580876); intron_variant(ENST00000619154, ENST00000293493, ENST00000314537, ENST00000347197, ENST00000339069, ENST00000577353, ENST00000580955, ENST00000583888, ENST00000634876, ENST00000398285, ENST00000582766, ENST00000352855, ENST00000634540); NMD_transcript_variant(ENST00000347197, ENST00000580955, ENST00000583888); non_coding_transcript_variant(ENST00000634876, ENST00000582766)
SIFT Annotation deleterious
SIFT Variant Effect deleterious(ENST00000352855, ENST00000634540, ENST00000577353, ENST00000293493, ENST00000314537, ENST00000398285, ENST00000339069)
PolyPhen Annotation benign
PolyPhen Variant Effect benign(ENST00000352855, ENST00000634540, ENST00000577353, ENST00000293493, ENST00000314537, ENST00000398285, ENST00000339069)
rSNP? Yes Link in rVarBase
Related Regulatory Elements TF binding region
Chromatin State Weak transcription;Bivalent Enhancer;Enhancers
No. of Marker's Association Results 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Amstadter, A. B.,2011 Acute UCLA PTSD-RI score B=-6.66, t=-2.46, Empirical P-value=0.02 B=-6.66, t=-2.46, Empirical P-value=0.02 This SNP was significantly related to PTSD symptom frequency...... This SNP was significantly related to PTSD symptom frequency. More... Significant

SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
CRHR1 corticotropin releasing hormone receptor 1 17q21.31 12(6/6/0)
MAPT-AS1 MAPT antisense RNA 1 17q21.31 Mapped by Literature SNP, Mapped by LD-proxy, rSNP target

SNPs in LD with rs17763104 (count: 6)
The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 6)

SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
DND1P1 No Adipose Subcutaneous cis GTEx