SNP Report

Basic Info

Name	rs242936 dbSNP Ensembl
Location	17:45821843 - 45821843(+)
Variant Seq	G
Ancestral Allele	G
Ref Seq	A
Minor Allele Frequence	0.0698882
Annotation	intron_variant; NMD_transcript_variant; non_coding_transcript_variant
Variant Effect	intron_variant(ENST00000398285, ENST00000577353, ENST00000580955, ENST00000634540, ENST00000339069, ENST00000314537, ENST00000347197, ENST00000293493, ENST00000582766, ENST00000634876, ENST00000352855, ENST00000583888, ENST00000619154); NMD_transcript_variant(ENST00000580955, ENST00000347197, ENST00000583888); non_coding_transcript_variant(ENST00000582766, ENST00000634876)
SIFT Annotation	deleterious
SIFT Variant Effect	deleterious(ENST00000339069, ENST00000314537, ENST00000398285, ENST00000580876, ENST00000577353, ENST00000634540, ENST00000352855, ENST00000293493)
PolyPhen Annotation	possibly_damaging; probably_damaging
PolyPhen Variant Effect	possibly_damaging(ENST00000314537); probably_damaging(ENST00000339069, ENST00000398285, ENST00000580876, ENST00000577353, ENST00000634540, ENST00000352855, ENST00000293493)
rSNP?	Yes Link in rVarBase
Related Regulatory Elements	n/a
Chromatin State	Weak transcription
No. of Marker's Association Results	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature

SNP related association results

Normal genetic study related association results (count: 1)

Reference	Phenotype	Statistical Values	Author Comments	Marker's Category
White, S.,2013	Post-hurricane PTSD symptoms	In EA sunsamples: B=-0.05, t=-0.51, P-value=0.61 In EA sunsamples: B=-0.05, t=-0.51, P-value=0.61	Not associated with higher post-hurricane PTSD symptoms. Not associated with higher post-hurricane PTSD symptoms.	Non-significant

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Association Results (Positive/Negative/Trend)
CRHR1	corticotropin releasing hormone receptor 1	17q21.31	12(6/6/0)
MAPT-AS1	MAPT antisense RNA 1	17q21.31	Mapped by Literature SNP, Mapped by LD-proxy, rSNP target

SNPs in LD with rs242936 (count: 3)

The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Annotation	r²[population]
rs171443	rs242936	synonymous_variant; upstream_gene_variant; intron_variant; non_coding_transcript_variant	1.0000[EUR]
rs4792825	rs242936	downstream_gene_variant; upstream_gene_variant; intron_variant; non_coding_transcript_variant	0.9811[EUR]
rs242950	rs242936	downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant	1.0000[EUR]; 0.8482[AMR]

SNP related eQTL (count: 1)

Gene Symbol	Gene Existed in PTSDgene?	Tissue	Trans/Cis	Source
DND1P1	No	Adipose Subcutaneous	cis	GTEx