PTSDgene database

SNP Report

Basic Info
Name rs242939 dbSNP Ensembl
Location 17:45818213 - 45818213(+)
Variant Seq T
Ancestral Allele T
Ref Seq C
Minor Allele Frequence 0.113019
Annotation downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant
Variant Effect downstream_gene_variant(ENST00000587305); intron_variant(ENST00000580955, ENST00000314537, ENST00000293493, ENST00000577353, ENST00000352855, ENST00000347197, ENST00000583888, ENST00000634876, ENST00000398285, ENST00000582766, ENST00000634540, ENST00000619154, ENST00000339069); NMD_transcript_variant(ENST00000580955, ENST00000347197, ENST00000583888); non_coding_transcript_variant(ENST00000634876, ENST00000582766)
SIFT Annotation tolerated
SIFT Variant Effect tolerated(ENST00000580955, ENST00000398285, ENST00000577353, ENST00000347197, ENST00000293493, ENST00000314537)
PolyPhen Annotation benign
PolyPhen Variant Effect benign(ENST00000580955, ENST00000398285, ENST00000577353, ENST00000347197, ENST00000293493, ENST00000314537)
rSNP? Yes Link in rVarBase
Related Regulatory Elements n/a
Chromatin State Weak transcription
No. of Marker's Association Results 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
White, S.,2013 Post-hurricane PTSD symptoms In EA sunsamples: B=-0.19, t=-0.57, P-value=0.57 In EA sunsamples: B=-0.19, t=-0.57, P-value=0.57 Not associated with higher post-hurricane PTSD symptoms. Not associated with higher post-hurricane PTSD symptoms. Non-significant


SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
CRHR1 corticotropin releasing hormone receptor 1 17q21.31 12(6/6/0)
MAPT-AS1 MAPT antisense RNA 1 17q21.31 Mapped by Literature SNP, Mapped by LD-proxy, rSNP target

SNPs in LD with rs242939 (count: 3)
The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 1)

LD-proxies (count: 2)


SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
DND1P1 No Adipose Subcutaneous cis GTEx