SNP Report
Basic Info
| Name | rs17763658 dbSNP Ensembl | ||
|---|---|---|---|
| Location | 17:45845274 - 45845274(+) | ||
| Variant Seq | A | ||
| Ancestral Allele | G | ||
| Ref Seq | G | ||
| Minor Allele Frequence | 0.090655 | ||
| Annotation | missense_variant; upstream_gene_variant; intron_variant; non_coding_transcript_variant | ||
| Variant Effect | missense_variant(ENST00000329196); upstream_gene_variant(ENST00000581125); intron_variant(ENST00000579599, ENST00000579244, ENST00000634876); non_coding_transcript_variant(ENST00000579599, ENST00000579244, ENST00000634876) | ||
| SIFT Annotation | tolerated | ||
| SIFT Variant Effect | tolerated(ENST00000329196) | ||
| PolyPhen Annotation | benign | ||
| PolyPhen Variant Effect | benign(ENST00000329196) | ||
| rSNP? | Yes Link in rVarBase | ||
| Related Regulatory Elements | n/a | ||
| Chromatin State | Weak transcription;Bivalent Enhancer | ||
| No. of Marker's Association Results | 1 (Positive: 0; Negative: 1; Trend: 0) | ||
| Source | Literature | ||
SNP related association results
| Reference | Phenotype | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|
| Amstadter, A. B.,2011 | Acute UCLA PTSD-RI score | B=3.90, t=1.19, Empirical P-value=0.26 B=3.90, t=1.19, Empirical P-value=0.26 | No significant result. No significant result. | Non-significant |
SNP related genes (count: 3)
| Approved Symbol | Approved Name | Location | No. of Association Results (Positive/Negative/Trend)  |
|---|---|---|---|
| CRHR1 | corticotropin releasing hormone receptor 1 | 17q21.31 | 12(6/6/0) |
| SPPL2C | signal peptide peptidase like 2C | 17q21.31 | Mapped by Literature SNP, Mapped by LD-proxy, rSNP target |
| MAPT-AS1 | MAPT antisense RNA 1 | 17q21.31 | Mapped by Literature SNP, Mapped by LD-proxy, rSNP target |
SNPs in LD with rs17763658 (count: 10)
Literature-origin SNPs (count: 0)
LD-proxies (count: 10)
SNP related eQTL (count: 1)