PTSDgene database

SNP Report

Basic Info
Name rs242924 dbSNP Ensembl
Location 17:45808001 - 45808001(+)
Variant Seq T
Ancestral Allele G
Ref Seq G
Minor Allele Frequence 0.436302
Annotation intron_variant; NMD_transcript_variant; non_coding_transcript_variant
Variant Effect intron_variant(ENST00000577353, ENST00000339069, ENST00000398285, ENST00000582766, ENST00000634876, ENST00000352855, ENST00000634540, ENST00000619154, ENST00000580955, ENST00000587305, ENST00000347197, ENST00000293493, ENST00000314537); NMD_transcript_variant(ENST00000580955, ENST00000347197); non_coding_transcript_variant(ENST00000582766, ENST00000634876, ENST00000587305)
SIFT Annotation tolerated
SIFT Variant Effect tolerated(ENST00000293493, ENST00000398285, ENST00000314537, ENST00000577353, ENST00000347197, ENST00000580955)
PolyPhen Annotation benign; possibly_damaging
PolyPhen Variant Effect benign(ENST00000293493, ENST00000398285, ENST00000314537, ENST00000577353); possibly_damaging(ENST00000347197, ENST00000580955)
rSNP? Yes Link in rVarBase
Related Regulatory Elements n/a
Chromatin State Weak transcription
No. of Marker's Association Results 2 (Positive: 0; Negative: 2; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 2)
Reference Phenotype Statistical Values Author Comments Marker's Category
White, S.,2013 Post-hurricane PTSD symptoms In EA sunsamples: B=-0.40, t=-1.62, P-value=0.11 In EA sunsamples: B=-0.40, t=-1.62, P-value=0.11 Not associated with higher post-hurricane PTSD symptoms. Not associated with higher post-hurricane PTSD symptoms. Non-significant
Binder, E. B.,2008 PTSD symptom severity No available detail information. No available detail information. It showed a non-significant main effect on PTSD symptom seve...... It showed a non-significant main effect on PTSD symptom severity. More... Non-significant
G*E study related association result (count: 1)
Reference Phenotype Environment Statistical Values Author Comments Marker's Category
Binder, E. B.,2008 PTSD Symptom Severity Child abuse No available detail information. No available detail information. It showed a non-significant interaction effect with child ab...... It showed a non-significant interaction effect with child abuse or non-child abuse trauma exposure on PTSD symptom severity. More... Non-significant


SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
CRHR1 corticotropin releasing hormone receptor 1 17q21.31 12(6/6/0)
MAPT-AS1 MAPT antisense RNA 1 17q21.31 Mapped by Literature SNP, Mapped by LD-proxy, rSNP target

SNPs in LD with rs242924 (count: 10)
The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 3)

LD-proxies (count: 7)


SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
DND1P1 No Adipose Subcutaneous cis GTEx