SNP Report
Basic Info
| Name | rs1799913 dbSNP Ensembl | ||
|---|---|---|---|
| Location | 11:18025708 - 18025708(+) | ||
| Variant Seq | A,T | ||
| Ancestral Allele | T | ||
| Ref Seq | G | ||
| Minor Allele Frequence | 0.321086 | ||
| Annotation | downstream_gene_variant; upstream_gene_variant; intron_variant; splice_region_variant; NMD_transcript_variant | ||
| Variant Effect | downstream_gene_variant(ENST00000528338); upstream_gene_variant(ENST00000525523, ENST00000525406); intron_variant(ENST00000417164, ENST00000250018); splice_region_variant(ENST00000417164, ENST00000250018); NMD_transcript_variant(ENST00000417164) | ||
| SIFT Annotation | tolerated | ||
| SIFT Variant Effect | tolerated(ENST00000265965, ENST00000525422, ENST00000528200) | ||
| PolyPhen Annotation | unknown; benign | ||
| PolyPhen Variant Effect | unknown(ENST00000524716); benign(ENST00000265965, ENST00000525422, ENST00000528200) | ||
| rSNP? | Yes Link in rVarBase | ||
| Related Regulatory Elements | Chromatin interactive region | ||
| Chromatin State | Weak transcription | ||
| No. of Marker's Association Results | 1 (Positive: 0; Negative: 1; Trend: 0) | ||
| Source | Literature | ||
SNP related association results
| Reference | Phenotype | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|
| Goenjian, A. K.,2012 | PTSD-RI (PTSD symptoms) | After adjusting for age, sex, exposure and environmental var...... After adjusting for age, sex, exposure and environmental variables, the family based variance component analyses of PTSD-RI with rs1799913: P-value=0.69, lod score=0.56. More... | No significant association was observed. No significant association was observed. | Non-significant |
SNP related genes (count: 2)
| Approved Symbol | Approved Name | Location | No. of Association Results (Positive/Negative/Trend)  |
|---|---|---|---|
| SERGEF | secretion regulating guanine nucleotide exchange factor | 11p14.3 | Mapped by LD-proxy, rSNP target |
| TPH1 | tryptophan hydroxylase 1 | 11p15.3-p14 | 5(1/4/0) |
SNPs in LD with rs1799913 (count: 46)
Literature-origin SNPs (count: 1)
LD-proxies (count: 45)
SNP related eQTL (count: 1)