PTSDgene database

Gene Report

Basic Info
Approved Symbol BDNF
Approved Name brain-derived neurotrophic factor
Name Alias neurotrophin
Location 11p14.1
Position chr11:27654893-27722058, -1
External Links HGNC: 1033
Entrez Gene: 627
Ensembl: ENSG00000176697
UCSC: uc009yje.3
No. of Association Results 19 (Positive: 4; Negative: 15; trend: 0)
Annotation Type Literature-origin, Mapped by Literature SNP, Mapped by LD-proxy, rSNP target
Gene related association results
Normal genetic study related association results (count: 19)
Reference Phenotype Marker Gene's Category
Bruenig, D.,2016 CAPS score rs6265 Non-significant
Li, R. H.,2016 Changes in PTSD severity between 6 and 12 months rs6265 Non-significant
Li, R. H.,2016 Changes in PTSD severity between 6 and 18 months rs6265 Non-significant
Li, R. H.,2016 Changes in PTSD severity between 12 and 18 months rs6265 Significant
van den Heuvel, L.,2016 PTSD diagnosis rs6265 Non-significant
van den Heuvel, L.,2016 CAPS score rs6265 Non-significant
Zhang, H.,2006 PTSD BDNF_5'region_G712A ; BDNF_exon_C270T ; rs6265 Non-significant
Zhang, H.,2006 Posttraumatic Stress Disorder G-712A-C270T-Val66Met, G-C-A,G-C-G,G-T-G,A-C-G,A-T-A,A-T-G Non-significant
Li, R. H.,2016 PCL-C Scores of the Subjects with Different Genotypes of BDNF Val66Met at 6 or 12 or 18 Months After the Earthquake rs6265 Significant
Dunn, E. C.,2014 Post Traumatic Growth (PTG) rs6265 Non-significant
Dunn, E. C.,2014 Post-traumatic stress symptoms (PTS) rs6265 Non-significant
Li, R. H.,2016 Prevalence of PTSD in the Subjects with Different BDNF Val66Met Genotypes at 6 or 12 or 18 Months After the Earthquake rs6265 Significant
Pivac, N.,2012 Psychotic symptoms in PTSD rs6265 Significant
Valente, N. L.,2011 PTSD rs6265 Non-significant
Wang, T.,2015 PTSD rs6265 Non-significant
Lee, Heon-Jeong,2006 PTSD rs6265 Non-significant
Solovieff, N.,2014 PTSD diagnosis rs2140887 Non-significant
Solovieff, N.,2014 PTSD severity rs1464896 Non-significant
La Greca, A. M.,2013 PTSD symptoms rs6265 Non-significant
G*E study related association result (count: 1)
Reference Phenotype Environment Marker Gene's Category
Dunn, E. C.,2014 Post Traumatic Growth (PTG) Hurricane exposure rs6265 Non-significant
Gene functional annotation
Gene related GO terms (count: 39)

Gene related KEGG pathways (count: 2)

Gene related interactors from protein-protein interactions data in PINA v2 (count: 9)