SNP Report
Basic Info
| Name | rs2140887 dbSNP Ensembl | ||
|---|---|---|---|
| Location | 11:28019800 - 28019800(+) | ||
| Variant Seq | G | ||
| Ancestral Allele | A | ||
| Ref Seq | A | ||
| Minor Allele Frequence | 0.390176 | ||
| Annotation | downstream_gene_variant; upstream_gene_variant | ||
| Variant Effect | downstream_gene_variant(ENST00000263181); upstream_gene_variant(ENST00000525309) | ||
| SIFT Annotation | tolerated | ||
| SIFT Variant Effect | tolerated(ENST00000263181) | ||
| PolyPhen Annotation | possibly_damaging | ||
| PolyPhen Variant Effect | possibly_damaging(ENST00000263181) | ||
| rSNP? | Yes Link in rVarBase | ||
| Related Regulatory Elements | TF binding region | ||
| Chromatin State | Weak transcription;Strong transcription | ||
| No. of Marker's Association Results | 1 (Positive: 0; Negative: 1; Trend: 0) | ||
| Source | Literature | ||
SNP related association results
| Reference | Phenotype | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|
| Solovieff, N.,2014 | PTSD diagnosis | P-value=0.012 P-value=0.012 | Achieved nominal levels of significance with PTSD diagnosis,...... Achieved nominal levels of significance with PTSD diagnosis, although was not significant after correction for multiple testing More... | Non-significant |
SNP related genes (count: 2)
| Approved Symbol | Approved Name | Location | No. of Association Results (Positive/Negative/Trend)  |
|---|---|---|---|
| BDNF | brain-derived neurotrophic factor | 11p14.1 | 19(4/15/0) |
| KIF18A | kinesin family member 18A | 11p14.1 | Mapped by Literature SNP, Mapped by LD-proxy, rSNP target |
SNPs in LD with rs2140887 (count: 53)
Literature-origin SNPs (count: 0)
LD-proxies (count: 53)
SNP related eQTL (count: 1)