PTSDgene database

Meta-analysis Report

Basic Info
Reference
Citation Wang, T. (2015). "Does BDNF Val66Met Polymorphism Confer Risk for Posttraumatic Stress Disorder?" Neuropsychobiology 71(3): 149-153.
Objective Evidence has indicated that BDNF (brain-derived neurotrophic factor) Val66Met genetic variant could be linked to the development of posttraumatic stress disorder (PTSD). However, clinical observations studying the BDNF polymorphism and the risk of PTSD yielded contradictory results. In this meta-analysis we evaluated the association between BDNF Val66Met and PTSD risk.
Study Type Candidate gene association study
Extract Database PubMed, Embase and Cochrane library online databases (An attempt to search more databases, PsycINFO,PsycARTICLES,CNKI.net,Scopus,Web of Science,and HuGENet, but no additional studies were added.)
Time Range 2006 to April 2014

Detail Info

Genetic result reported by this study
Normal genetic result reported by this study (count: 1)
Marker Phenotype Related Gene Statistical Values Author Comments Marker's Category
rs6265 PTSD BDNF Our study did not found a significant overall effect of BDNF Val66Met on the susceptibility to PTSD under various genetic models. Their pooled analyses did not demonstrate a significant over...... Their pooled analyses did not demonstrate a significant overall effect of the BDNF Val66Met allele on the development of PTSD within the selected genetic models. More... Non-significant