Wang, T.,2015 PMID: 25925851
||Wang, T. (2015). "Does BDNF Val66Met Polymorphism Confer Risk for Posttraumatic Stress Disorder?" Neuropsychobiology 71(3): 149-153.
||Evidence has indicated that BDNF (brain-derived neurotrophic factor) Val66Met genetic variant could be linked to the development of posttraumatic stress disorder (PTSD). However, clinical observations studying the BDNF polymorphism and the risk of PTSD yielded contradictory results. In this meta-analysis we evaluated the association between BDNF Val66Met and PTSD risk.
||Candidate gene association study
||PubMed, Embase and Cochrane library online databases (An attempt to search more databases, PsycINFO,PsycARTICLES,CNKI.net,Scopus,Web of Science,and HuGENet, but no additional studies were added.)
||2006 to April 2014
Genetic result reported by this study
Normal genetic result reported by this study (count: 1)
||Our study did not found a significant overall effect of BDNF Val66Met on the susceptibility to PTSD under various genetic models.
Their pooled analyses did not demonstrate a significant over......
Their pooled analyses did not demonstrate a significant overall effect of the BDNF Val66Met allele on the development of PTSD within the selected genetic models.