PTSDgene database

Study Report

Study Information
Basic Info
Reference Bruenig, D.,2017(b) PMID: 28465168
Citation Bruenig, D., et al. (2017)."Nitric oxide pathway genes (NOS1AP and NOS1) are involved in PTSD severity, depression, anxiety, stress and resilience." Gene 625: 42-48.
Phenotype PTSD severity
Trauma Vietnam combat
Study Design Case-control
Study Type Candidate gene association study
Sample Size 159 cases, 140 controls
SNP/Marker Size 65 SNPs
Predominant Ethnicity Caucasian
Population Australian
Gender Not mentioned
Age Case: mean age=68.47 years,SD=4.16, Control: mean age=69.13 years,SD=4.14

Detail Info

Genetic result reported by this study
Normal genetic result reported by this study (count: 62)
Marker Phenotype Related Gene Statistical Values Author Comments Marker's Category
rs1337062 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs10918671 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs12074902 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs1415259 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs10494366 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs16857031 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs12029454 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs4657178 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs10458392 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs10753789 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs10800465 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs1572495 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs164148 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs4526593 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs4657154 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs449908 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs4657164 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs945708 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs16857019 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs10918936 CAPS score NOS1AP ANOVA: P-value=0.042. Independent t-tests (dominant model): P-value=0.023. This SNP was associated with PTSD severity within the PTSD g...... This SNP was associated with PTSD severity within the PTSD group. More... Significant
rs10918762 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs12116744 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs10919025 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs12122048 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs12027674 CAPS score NOS1AP ANOVA: P-value=0.022. Independent t-tests (dominant model): P-value=0.014. This SNP was associated with PTSD severity within the PTSD g...... This SNP was associated with PTSD severity within the PTSD group. More... Significant
rs7528328 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs7546353 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs6676737 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs3897374 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs6659953 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs6677529 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs6683968 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs6677052 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs2819316 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs2819322 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs12742393 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs10157390 CAPS score NOS1AP ANOVA: P-value=0.019. Independent t-tests (dominant model): P-value=0.010. This SNP was associated with PTSD severity within the PTSD g...... This SNP was associated with PTSD severity within the PTSD group. More... Significant
rs347311 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs347282 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs9661075 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs347300 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs17460657 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs12725553 CAPS score NOS1AP ANOVA: P-value=0.038. Independent t-tests (dominant model): P-value=0.028. This SNP was associated with PTSD severity within the PTSD g...... This SNP was associated with PTSD severity within the PTSD group. More... Significant
rs111479527 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs115298183 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs7959232 CAPS score NOS1 ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs1353939 CAPS score NOS1 ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs9658570 CAPS score NOS1 ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs6700867 CAPS score NOS1AP ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs3825102 CAPS score NOS1 ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs11068428 CAPS score NOS1 ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs2291908 CAPS score NOS1 ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs816353 CAPS score NOS1 ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs7295972 CAPS score NOS1 ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs11068445 CAPS score NOS1 ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs532967 CAPS score NOS1 ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs10744891 CAPS score NOS1 ANOVA: P-value=0.005. Independent t-tests (dominant model): P-value=0.007. This SNP was associated with PTSD severity within the PTSD g...... This SNP was associated with PTSD severity within the PTSD group. The rs10744891 SNP remained associated with PTSD severity after correction for multiple testing. More... Significant
rs482555 CAPS score NOS1 ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs474523 CAPS score NOS1 ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs2077171 CAPS score NOS1 ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs549098 CAPS score NOS1 ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant
rs61938733 CAPS score NOS1 ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant

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Last update: April 1, 2018