SNP Report
Basic Info
| Name | rs12725553 dbSNP Ensembl | ||
|---|---|---|---|
| Location | 1:162198326 - 162198326(+) | ||
| Variant Seq | A | ||
| Ancestral Allele | G | ||
| Ref Seq | G | ||
| Minor Allele Frequence | 0.46266 | ||
| Annotation | intron_variant; NMD_transcript_variant | ||
| Variant Effect | intron_variant(ENST00000430120, ENST00000530878, ENST00000361897); NMD_transcript_variant(ENST00000430120) | ||
| SIFT Annotation | tolerated | ||
| SIFT Variant Effect | tolerated(ENST00000530878, ENST00000361897, ENST00000430120) | ||
| PolyPhen Annotation | benign; possibly_damaging | ||
| PolyPhen Variant Effect | benign(ENST00000530878); possibly_damaging(ENST00000361897, ENST00000430120) | ||
| rSNP? | Yes Link in rVarBase | ||
| Related Regulatory Elements | n/a | ||
| Chromatin State | Enhancers;Weak transcription;Flanking Active TSS | ||
| No. of Marker's Association Results | 1 (Positive: 1; Negative: 0; Trend: 0) | ||
| Source | Literature | ||
SNP related association results
| Reference | Phenotype | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|
| Bruenig, D.,2017(b) | CAPS score | ANOVA: P-value=0.038. Independent t-tests (dominant model): ...... ANOVA: P-value=0.038. Independent t-tests (dominant model): P-value=0.028. More... | This SNP was associated with PTSD severity within the PTSD g...... This SNP was associated with PTSD severity within the PTSD group. More... | Significant |
SNP related genes (count: 1)
| Approved Symbol | Approved Name | Location | No. of Association Results (Positive/Negative/Trend)  |
|---|---|---|---|
| NOS1AP | nitric oxide synthase 1 adaptor protein | 1q23.3 | 3(3/0/0) |
SNPs in LD with rs12725553 (count: 12)
Literature-origin SNPs (count: 2)
LD-proxies (count: 10)
SNP related eQTL (count: 1)