PTSDgene database

Pathway Enrichment Analysis Protein-Protein Interaction Analysis

SNP Report

Basic Info

Name	rs61938733 dbSNP Ensembl
Location	12:117349366 - 117349366(+)
Variant Seq	A
Ancestral Allele	G
Ref Seq	G
Minor Allele Frequence	0.0155751
Annotation	intron_variant; non_coding_transcript_variant
Variant Effect	intron_variant(ENST00000618760, ENST00000549189, ENST00000317775, ENST00000477584); non_coding_transcript_variant(ENST00000549189, ENST00000477584)
SIFT Annotation	deleterious_-_low_confidence
SIFT Variant Effect	deleterious_-_low_confidence(ENST00000317775, ENST00000338101, ENST00000618760, ENST00000344089)
PolyPhen Annotation	probably_damaging
PolyPhen Variant Effect	probably_damaging(ENST00000317775, ENST00000338101, ENST00000618760, ENST00000344089)
rSNP?	Yes Link in rVarBase
Related Regulatory Elements	n/a
Chromatin State	Weak transcription;Enhancers
No. of Marker's Association Results	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature

SNP related association results

Normal genetic study related association results (count: 1)

Reference	Phenotype	Statistical Values	Author Comments	Marker's Category
Bruenig, D.,2017(b)	CAPS score	ANOVA: P-value>0.05 ANOVA: P-value>0.05	This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity.	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Association Results (Positive/Negative/Trend)
NOS1	nitric oxide synthase 1	12q24.22	1(1/0/0)

SNPs in LD with rs61938733 (count: 0)

SNP related eQTL (count: 1)

Gene Symbol	Gene Existed in PTSDgene?	Tissue	Trans/Cis	Source
RP11-707O23.5	No	Adipose Subcutaneous	cis	GTEx