SNP Report
Basic Info
| Name | rs4657178 dbSNP Ensembl | ||
|---|---|---|---|
| Location | 1:162240820 - 162240820(+) | ||
| Variant Seq | T | ||
| Ancestral Allele | C | ||
| Ref Seq | C | ||
| Minor Allele Frequence | 0.40016 | ||
| Annotation | intron_variant; NMD_transcript_variant | ||
| Variant Effect | intron_variant(ENST00000530878, ENST00000361897, ENST00000430120); NMD_transcript_variant(ENST00000430120) | ||
| SIFT Annotation | tolerated | ||
| SIFT Variant Effect | tolerated(ENST00000530878, ENST00000361897, ENST00000430120) | ||
| PolyPhen Annotation | benign; possibly_damaging | ||
| PolyPhen Variant Effect | benign(ENST00000530878); possibly_damaging(ENST00000361897, ENST00000430120) | ||
| rSNP? | Yes Link in rVarBase | ||
| Related Regulatory Elements | Chromatin interactive region | ||
| Chromatin State | Weak transcription;Enhancers | ||
| No. of Marker's Association Results | 2 (Positive: 0; Negative: 2; Trend: 0) | ||
| Source | Literature | ||
SNP related association results
| Reference | Phenotype | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|
| Bruenig, D.,2017(b) | CAPS score | ANOVA: P-value>0.05 ANOVA: P-value>0.05 | This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. | Non-significant |
| Lawford, B. R.,2013 | PTSD | Allele frequencies: X2=0.125, P-value=0.724, OR=...... Allele frequencies: X2=0.125, P-value=0.724, OR=1.07, 95%CI(0.62-1.39). More... | No significant signals was observed about this SNP. No significant signals was observed about this SNP. | Non-significant |
SNP related genes (count: 1)
| Approved Symbol | Approved Name | Location | No. of Association Results (Positive/Negative/Trend)  |
|---|---|---|---|
| NOS1AP | nitric oxide synthase 1 adaptor protein | 1q23.3 | 3(3/0/0) |
SNPs in LD with rs4657178 (count: 5)
Literature-origin SNPs (count: 0)
LD-proxies (count: 5)
SNP related eQTL (count: 1)