PTSDgene database

SNP Report

Basic Info
Name rs12116744 dbSNP Ensembl
Location 1:162210666 - 162210666(+)
Variant Seq A
Ancestral Allele G
Ref Seq G
Minor Allele Frequence 0.326078
Annotation intron_variant; NMD_transcript_variant
Variant Effect intron_variant(ENST00000361897, ENST00000430120, ENST00000530878); NMD_transcript_variant(ENST00000430120)
SIFT Annotation tolerated
SIFT Variant Effect tolerated(ENST00000530878, ENST00000361897, ENST00000430120)
PolyPhen Annotation benign; possibly_damaging
PolyPhen Variant Effect benign(ENST00000530878); possibly_damaging(ENST00000361897, ENST00000430120)
rSNP? Yes Link in rVarBase
Related Regulatory Elements n/a
Chromatin State Weak transcription;Enhancers;Genic enhancers
No. of Marker's Association Results 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Bruenig, D.,2017(b) CAPS score ANOVA: P-value>0.05 ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant


SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
NOS1AP nitric oxide synthase 1 adaptor protein 1q23.3 3(3/0/0)

SNPs in LD with rs12116744 (count: 24)
The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 24)


SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
CRHR1 Yes Adipose Subcutaneous cis GTEx