PTSDgene database

SNP Report

Basic Info
Name rs164148 dbSNP Ensembl
Location 1:162368695 - 162368695(+)
Variant Seq G
Ancestral Allele A
Ref Seq A
Minor Allele Frequence 0.278954
Annotation downstream_gene_variant; 3_prime_UTR_variant; intron_variant; NMD_transcript_variant
Variant Effect downstream_gene_variant(ENST00000430120, ENST00000464284, ENST00000367935, ENST00000454693, ENST00000530878); 3_prime_UTR_variant(ENST00000361897, ENST00000493151); intron_variant(ENST00000367932, ENST00000420220, ENST00000431696); NMD_transcript_variant(ENST00000367932)
SIFT Annotation deleterious
SIFT Variant Effect deleterious(ENST00000620601, ENST00000367935)
PolyPhen Annotation benign
PolyPhen Variant Effect benign(ENST00000620601, ENST00000367935)
rSNP? Yes Link in rVarBase
Related Regulatory Elements Chromatin interactive region
Chromatin State Strong transcription;Weak transcription;Genic enhancers;Enhancers
No. of Marker's Association Results 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Bruenig, D.,2017(b) CAPS score ANOVA: P-value>0.05 ANOVA: P-value>0.05 This SNP was not associated with PTSD severity. This SNP was not associated with PTSD severity. Non-significant

SNP related genes (count: 3)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
NOS1AP nitric oxide synthase 1 adaptor protein 1q23.3 3(3/0/0)
C1orf226 chromosome 1 open reading frame 226 1q23.3 Mapped by Literature SNP, Mapped by LD-proxy, rSNP target
C1orf111 chromosome 1 open reading frame 111 1q23.3 Mapped by Literature SNP, Mapped by LD-proxy

SNPs in LD with rs164148 (count: 3)
The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 3)

SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
SERGEF Yes Adipose Subcutaneous cis GTEx