PTSDgene database

SNP Report

Basic Info
Name rs10482605 dbSNP Ensembl
Location 5:143403956 - 143403956(+)
Variant Seq G
Ancestral Allele A
Ref Seq A
Minor Allele Frequence 0.0982428
Annotation upstream_gene_variant; intron_variant
Variant Effect upstream_gene_variant(ENST00000415690, ENST00000510170, ENST00000424646, ENST00000231509, ENST00000502500, ENST00000394464, ENST00000508760, ENST00000623204); intron_variant(ENST00000503201, ENST00000343796, ENST00000502892, ENST00000514699, ENST00000504572, ENST00000394466)
SIFT Annotation tolerated
SIFT Variant Effect tolerated(ENST00000424646, ENST00000504572, ENST00000503201, ENST00000231509, ENST00000394466, ENST00000343796, ENST00000394464, ENST00000415690)
PolyPhen Annotation benign
PolyPhen Variant Effect benign(ENST00000424646, ENST00000504572, ENST00000503201, ENST00000231509, ENST00000394466, ENST00000343796, ENST00000394464, ENST00000415690)
rSNP? Yes Link in rVarBase
Related Regulatory Elements TF binding region;Chromatin interactive region
Chromatin State Active TSS;Bivalent/Poised TSS;Transcr. at gene 5' nd 3';Weak transcription
No. of Marker's Association Results 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Lian, Y.,2014 PTSD Logistic regression analysis (after adjusting for age): gen...... Logistic regression analysis (after adjusting for age): genotype P-value=0.096, allele P-value=0.087. More... The rs10482605 is not associated with PTSD. The rs10482605 is not associated with PTSD. Non-significant


SNP related genes (count: 3)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
NR3C1 nuclear receptor subfamily 3 group C member 1 5q31-q32 6(2/4/0)
H2AFX H2A histone family member X 11q23.3 rSNP target
ARHGAP26 Rho GTPase activating protein 26 5q31 rSNP target

SNPs in LD with rs10482605 (count: 0)

SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
CRHR1-IT1 Yes Adipose Subcutaneous cis GTEx