PTSDgene database

Pathway Enrichment Analysis Protein-Protein Interaction Analysis

SNP Report

Basic Info

Name	rs10482605 dbSNP Ensembl
Location	5:143403956 - 143403956(+)
Variant Seq	G
Ancestral Allele	A
Ref Seq	A
Minor Allele Frequence	0.0982428
Annotation	upstream_gene_variant; intron_variant
Variant Effect	upstream_gene_variant(ENST00000415690, ENST00000510170, ENST00000424646, ENST00000231509, ENST00000502500, ENST00000394464, ENST00000508760, ENST00000623204); intron_variant(ENST00000503201, ENST00000343796, ENST00000502892, ENST00000514699, ENST00000504572, ENST00000394466)
SIFT Annotation	tolerated
SIFT Variant Effect	tolerated(ENST00000424646, ENST00000504572, ENST00000503201, ENST00000231509, ENST00000394466, ENST00000343796, ENST00000394464, ENST00000415690)
PolyPhen Annotation	benign
PolyPhen Variant Effect	benign(ENST00000424646, ENST00000504572, ENST00000503201, ENST00000231509, ENST00000394466, ENST00000343796, ENST00000394464, ENST00000415690)
rSNP?	Yes Link in rVarBase
Related Regulatory Elements	TF binding region;Chromatin interactive region
Chromatin State	Active TSS;Bivalent/Poised TSS;Transcr. at gene 5' nd 3';Weak transcription
No. of Marker's Association Results	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature

SNP related association results

Normal genetic study related association results (count: 1)

Reference	Phenotype	Statistical Values	Author Comments	Marker's Category
Lian, Y.,2014	PTSD	Logistic regression analysis (after adjusting for age): gen...... Logistic regression analysis (after adjusting for age): genotype P-value=0.096, allele P-value=0.087. More...	The rs10482605 is not associated with PTSD. The rs10482605 is not associated with PTSD.	Non-significant

SNP related genes (count: 3)

Approved Symbol	Approved Name	Location	No. of Association Results (Positive/Negative/Trend)
NR3C1	nuclear receptor subfamily 3 group C member 1	5q31-q32	6(2/4/0)
H2AFX	H2A histone family member X	11q23.3	rSNP target
ARHGAP26	Rho GTPase activating protein 26	5q31	rSNP target

SNPs in LD with rs10482605 (count: 0)

SNP related eQTL (count: 1)

Gene Symbol	Gene Existed in PTSDgene?	Tissue	Trans/Cis	Source
CRHR1-IT1	Yes	Adipose Subcutaneous	cis	GTEx