PTSDgene database

SNP Report

Basic Info
Name rs7701443 dbSNP Ensembl
Location 5:143413085 - 143413085(+)
Variant Seq G
Ancestral Allele A
Ref Seq A
Minor Allele Frequence 0.460463
Annotation intron_variant; non_coding_transcript_variant
Variant Effect intron_variant(ENST00000505058, ENST00000343796, ENST00000504572, ENST00000503701); non_coding_transcript_variant(ENST00000505058, ENST00000503701)
SIFT Annotation tolerated
SIFT Variant Effect tolerated(ENST00000424646, ENST00000504572, ENST00000503201, ENST00000231509, ENST00000394466, ENST00000343796, ENST00000394464, ENST00000415690)
PolyPhen Annotation benign
PolyPhen Variant Effect benign(ENST00000424646, ENST00000504572, ENST00000503201, ENST00000231509, ENST00000394466, ENST00000343796, ENST00000394464, ENST00000415690)
rSNP? Yes Link in rVarBase
Related Regulatory Elements Chromatin interactive region
Chromatin State Weak transcription;Enhancers
No. of Marker's Association Results 2 (Positive: 0; Negative: 2; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 2)
Reference Phenotype Statistical Values Author Comments Marker's Category
Solovieff, N.,2014 PTSD diagnosis P-value=0.059 P-value=0.059 Achieved nominal levels of significance with PTSD diagnosis,...... Achieved nominal levels of significance with PTSD diagnosis, although was not significant after correction for multiple testing More... Non-significant
Solovieff, N.,2014 PTSD severity P-value=0.209 P-value=0.209 Achieved nominal levels of significance with PTSD severity, ...... Achieved nominal levels of significance with PTSD severity, although was not significant after correction for multiple testing More... Non-significant


SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
NR3C1 nuclear receptor subfamily 3 group C member 1 5q31-q32 6(2/4/0)

SNPs in LD with rs7701443 (count: 0)

SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
CRHR1-IT1 Yes Adipose Subcutaneous cis GTEx