SNP Report
Basic Info
| Name | rs7701443 dbSNP Ensembl | ||
|---|---|---|---|
| Location | 5:143413085 - 143413085(+) | ||
| Variant Seq | G | ||
| Ancestral Allele | A | ||
| Ref Seq | A | ||
| Minor Allele Frequence | 0.460463 | ||
| Annotation | intron_variant; non_coding_transcript_variant | ||
| Variant Effect | intron_variant(ENST00000505058, ENST00000343796, ENST00000504572, ENST00000503701); non_coding_transcript_variant(ENST00000505058, ENST00000503701) | ||
| SIFT Annotation | tolerated | ||
| SIFT Variant Effect | tolerated(ENST00000424646, ENST00000504572, ENST00000503201, ENST00000231509, ENST00000394466, ENST00000343796, ENST00000394464, ENST00000415690) | ||
| PolyPhen Annotation | benign | ||
| PolyPhen Variant Effect | benign(ENST00000424646, ENST00000504572, ENST00000503201, ENST00000231509, ENST00000394466, ENST00000343796, ENST00000394464, ENST00000415690) | ||
| rSNP? | Yes Link in rVarBase | ||
| Related Regulatory Elements | Chromatin interactive region | ||
| Chromatin State | Weak transcription;Enhancers | ||
| No. of Marker's Association Results | 2 (Positive: 0; Negative: 2; Trend: 0) | ||
| Source | Literature | ||
SNP related association results
| Reference | Phenotype | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|
| Solovieff, N.,2014 | PTSD diagnosis | P-value=0.059 P-value=0.059 | Achieved nominal levels of significance with PTSD diagnosis,...... Achieved nominal levels of significance with PTSD diagnosis, although was not significant after correction for multiple testing More... | Non-significant |
| Solovieff, N.,2014 | PTSD severity | P-value=0.209 P-value=0.209 | Achieved nominal levels of significance with PTSD severity, ...... Achieved nominal levels of significance with PTSD severity, although was not significant after correction for multiple testing More... | Non-significant |
SNP related genes (count: 1)
| Approved Symbol | Approved Name | Location | No. of Association Results (Positive/Negative/Trend)  |
|---|---|---|---|
| NR3C1 | nuclear receptor subfamily 3 group C member 1 | 5q31-q32 | 6(2/4/0) |
SNPs in LD with rs7701443 (count: 0)
SNP related eQTL (count: 1)