PTSDgene database

Study Report

Study Information
Basic Info
Reference
Citation Hauer, D., et al. (2011). "Relationship of a common polymorphism of the glucocorticoid receptor gene to traumatic memories and posttraumatic stress disorder in patients after intensive care therapy." Crit Care Med 39(4): 643-650.
Phenotype PTSD stress symptom scores
Trauma Cardiac surgery and intensive care unit treatment
Study Design Cross-sectional study
Study Type Candidate gene association study
Sample Size 126 samples
SNP/Marker Size 1 Variant
Predominant Ethnicity Caucasian
Population Germany
Gender 96 males, 30 females
Age BclI G allele carriers: mean age=67.1 years, SD=10.8. Heterozygous carriers or noncarriers of the allele: mean age=65.8 years, SD=9.3

Detail Info

Genetic result reported by this study
Normal genetic result reported by this study (count: 1)
Marker Phenotype Related Gene Statistical Values Author Comments Marker's Category
GR_intron 2_Bcl1 PTSD stress symptom scores NR3C1 1 week post-ICU: P-value=0.02 Homozygous BclI G allele carriers are at risk for posttrauma...... Homozygous BclI G allele carriers are at risk for posttraumatic stress disorder symptoms after cardiac surgery and intensive care unit therapy. More... Significant