PTSDgene database

SNP Report

Basic Info
Name rs9534507 dbSNP Ensembl
Location 13:46887599 - 46887599(+)
Variant Seq G
Ancestral Allele A
Ref Seq A
Minor Allele Frequence 0.0405351
Annotation intron_variant
Variant Effect intron_variant(ENST00000378688, ENST00000542664, ENST00000543956)
SIFT Annotation tolerated
SIFT Variant Effect tolerated(ENST00000542664, ENST00000543956, ENST00000378688)
PolyPhen Annotation benign
PolyPhen Variant Effect benign(ENST00000542664, ENST00000543956, ENST00000378688)
rSNP? Yes Link in rVarBase
Related Regulatory Elements n/a
Chromatin State Weak transcription;Strong transcription
No. of Marker's Association Results 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Solovieff, N.,2014 PTSD severity P-value=0.027 P-value=0.027 Achieved nominal levels of significance with PTSD severity, ...... Achieved nominal levels of significance with PTSD severity, although was not significant after correction for multiple testing More... Non-significant

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 13q14-q21 4(2/2/0)

SNPs in LD with rs9534507 (count: 15)
The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 15)

SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
RP11-707O23.5 No Adipose Subcutaneous cis GTEx