Gene Report

Basic Info

Approved Symbol	FAAH
Symbol Alias	FAAH-1
Approved Name	fatty acid amide hydrolase
Location	1p35-p34
Position	chr1:46394265-46413848, 1
External Links	HGNC: 3553 Entrez Gene: 2166 Ensembl: ENSG00000117480 UCSC: uc001cpu.2
No. of Association Results	8 (Positive: 3; Negative: 5; trend: 0)
Annotation Type	Literature-origin, Mapped by Literature SNP, Mapped by LD-proxy, rSNP target

Gene related association results

Normal genetic study related association results (count: 8)

Reference	Phenotype	Marker	Gene's Category
Spagnolo, P. A.,2016	PTSD symptoms	rs324420	Non-significant
Spagnolo, P. A.,2016	PTSD hyperarousal symptoms	rs324420	Significant
Spagnolo, P. A.,2016	PTSD re-experiencing symptoms	rs324420	Non-significant
Spagnolo, P. A.,2016	PTSD avoidance symptoms	rs324420	Non-significant
Pardini, M.,2012	Arousal symptoms	rs2295633	Non-significant
Pardini, M.,2012	Avoidance symptoms	rs2295633	Non-significant
Pardini, M.,2012	PTSD	rs2295633 ; rs324419 ; rs324420 ; rs3766246 ; rs6703669 ; rs7524148 ; rs913168	Significant
Pardini, M.,2012	Reexperiencing symptoms	rs2295633	Significant

Gene functional annotation

Gene related GO terms (count: 11)

ID	Name	Type	Evidence[PMID]	No. of Genes in PTSDgene
GO:0044281	small molecule metabolic process	biological process	TAS	38
GO:0047372	acylglycerol lipase activity	molecular function	IEA	1
GO:0005515	protein binding	molecular function	IPI[25416956]	169
GO:0005856	cytoskeleton	cellular component	IEA	12
GO:0016021	integral component of membrane	cellular component	IEA	56
GO:0009062	fatty acid catabolic process	biological process	IDA[9122178]	1
GO:0017064	fatty acid amide hydrolase activity	molecular function	IDA[9122178]	1
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	molecular function	IEA	1
GO:0031090	organelle membrane	cellular component	ISS	1
GO:0019369	arachidonic acid metabolic process	biological process	TAS	3
GO:0005789	endoplasmic reticulum membrane	cellular component	TAS	13

Gene related KEGG pathways (count: 0)

Gene related interactors from protein-protein interactions data in PINA v2 (count: 0)