SNP Report

Basic Info

Name	rs913168 dbSNP Ensembl
Location	1:46392904 - 46392904(+)
Variant Seq	C
Ancestral Allele	C
Ref Seq	T
Minor Allele Frequence	0.419728
Annotation	upstream_gene_variant
Variant Effect	upstream_gene_variant(ENST00000493735, ENST00000468718, ENST00000243167)
SIFT Annotation	tolerated
SIFT Variant Effect	tolerated(ENST00000474844, ENST00000537428)
PolyPhen Annotation	benign
PolyPhen Variant Effect	benign(ENST00000474844, ENST00000537428)
rSNP?	Yes Link in rVarBase
Related Regulatory Elements	TF binding region
Chromatin State	Active TSS;Flanking Active TSS;ZNF genes & repeats;Weak transcription
No. of Marker's Association Results	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature

SNP related association results

Normal genetic study related association results (count: 1)

Reference	Phenotype	Statistical Values	Author Comments	Marker's Category
Pardini, M.,2012	PTSD	C/- compared with T/T: In TPBI subjects without vmPFC lesi...... C/- compared with T/T: In TPBI subjects without vmPFC lesions: P-value= 0.18. In the vmPFC lesion group: P-value= 0.86. More...	No significant difference in PTSD prevalence between genotyp...... No significant difference in PTSD prevalence between genotypes in both subjects. More...	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Association Results (Positive/Negative/Trend)
FAAH	fatty acid amide hydrolase	1p35-p34	8(3/5/0)

SNPs in LD with rs913168 (count: 11)

The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Annotation	r²[population]
rs12075550	rs913168	downstream_gene_variant; upstream_gene_variant	0.9347[EUR]
rs11802866	rs913168	intron_variant; NMD_transcript_variant	0.8516[EUR]
rs11211271	rs913168	upstream_gene_variant	0.9035[EUR]
rs10252	rs913168	downstream_gene_variant; 3_prime_UTR_variant; NMD_transcript_variant	0.9347[EUR]
rs12562440	rs913168	downstream_gene_variant; intron_variant; NMD_transcript_variant	0.8159[EUR]
rs4660925	rs913168	upstream_gene_variant	0.9945[EUR]
rs12073998	rs913168	upstream_gene_variant	0.9198[EUR]
rs56733721	rs913168	downstream_gene_variant	0.9508[EUR]
rs11804189	rs913168	downstream_gene_variant	0.9508[EUR]
rs2145409	rs913168	downstream_gene_variant; intron_variant; NMD_transcript_variant	0.8519[EUR]
rs3863641	rs913168	upstream_gene_variant	0.9198[EUR]

SNP related eQTL (count: 1)

Gene Symbol	Gene Existed in PTSDgene?	Tissue	Trans/Cis	Source
CRHR1	Yes	Adipose Subcutaneous	cis	GTEx