PTSDgene database

SNP Report

Basic Info
Name rs913168 dbSNP Ensembl
Location 1:46392904 - 46392904(+)
Variant Seq C
Ancestral Allele C
Ref Seq T
Minor Allele Frequence 0.419728
Annotation upstream_gene_variant
Variant Effect upstream_gene_variant(ENST00000493735, ENST00000468718, ENST00000243167)
SIFT Annotation tolerated
SIFT Variant Effect tolerated(ENST00000474844, ENST00000537428)
PolyPhen Annotation benign
PolyPhen Variant Effect benign(ENST00000474844, ENST00000537428)
rSNP? Yes Link in rVarBase
Related Regulatory Elements TF binding region
Chromatin State Active TSS;Flanking Active TSS;ZNF genes & repeats;Weak transcription
No. of Marker's Association Results 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Pardini, M.,2012 PTSD C/- compared with T/T: In TPBI subjects without vmPFC lesi...... C/- compared with T/T: In TPBI subjects without vmPFC lesions: P-value= 0.18. In the vmPFC lesion group: P-value= 0.86. More... No significant difference in PTSD prevalence between genotyp...... No significant difference in PTSD prevalence between genotypes in both subjects. More... Non-significant

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
FAAH fatty acid amide hydrolase 1p35-p34 8(3/5/0)

SNPs in LD with rs913168 (count: 11)
The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 11)

SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
CRHR1 Yes Adipose Subcutaneous cis GTEx