PTSDgene database

SNP Report

Basic Info
Name rs7524148 dbSNP Ensembl
Location 1:46413119 - 46413119(+)
Variant Seq A
Ancestral Allele G
Ref Seq G
Annotation downstream_gene_variant; missense_variant; intron_variant; splice_region_variant; NMD_transcript_variant
Variant Effect downstream_gene_variant(ENST00000493735, ENST00000493636, ENST00000489366); missense_variant(ENST00000243167); intron_variant(ENST00000484697); splice_region_variant(ENST00000484697); NMD_transcript_variant(ENST00000484697)
SIFT Annotation deleterious
SIFT Variant Effect deleterious(ENST00000243167)
PolyPhen Annotation probably_damaging
PolyPhen Variant Effect probably_damaging(ENST00000243167)
rSNP? Yes Link in rVarBase
Related Regulatory Elements Chromatin interactive region
Chromatin State Weak transcription;Strong transcription;Enhancers;Bivalent Enhancer;Genic enhancers
No. of Marker's Association Results 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Pardini, M.,2012 PTSD No detail information No detail information No significant difference in PTSD prevalence between genotyp...... No significant difference in PTSD prevalence between genotypes in both subjects. More... Non-significant

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
FAAH fatty acid amide hydrolase 1p35-p34 8(3/5/0)

SNPs in LD with rs7524148 (count: 0)

SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
CRHR1 Yes Adipose Subcutaneous cis GTEx